Antibiotic Sensitivity Pattern of Salmonella typhi in Children of Typhoid Fever Aged between 6 Months to 18 Years in a Tertiary Care Hospital, Chittagong, Bangladesh
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 12
Abstract
Abstract: This cross sectional study was carried out in the Pediatric & Medicine wards of Chittagong Medical College Hospital (CMCH), Chittagong during the period between July 2012 and June 2013, the study was aimed to identify antibiotic sensitivity pattern of Salmonella typhi among children of typhoid fever in a tertiary care hospital. We selected 150 suspected cases of typhoid fever (age >6 months to18years) admitted in the above mentioned hospital and enrolled in this study. Majority (56.7%) of the patients belonged to 1-5 years of age and male to female ratio was 1.2:1. More than a half (56.0%) of the patients came from rural area. Blood C/S for salmonella typhi was found positive in 16(10.7%) cases and out of which only 1(6.25%) received typhoid vaccination. In the investigation, mean Hb was found 10.78±.55 g/dl with range from 5 to 145 g/dl. Mean TC was 13018.44±6510.33/cu mm with range from 1060 to 42000 /cu mm. Mean N was found 67.78±15.61% with range from 25 to 92%. Mean L was 27.59±15.24% with range from 6 to 72 %. Mean M was 2.57±0.93 % with range from 1 to 6 %. Mean E was 1.68±0.87 % with range from 0 to 6 %. Mean B was 0.31±0.54 % with range from 0 to 2 %. Antibiotic sensitivity among culture positive patients showed that Azithromycin, Ceftriaxone and Imipenam were 100% sensitive followed by Cefixime 68.8%%, Nalidixic acid (Intermediate sensitive) 56.3%, Chloramphenicol 38.35%, Ciprofloxacin (Intermediate sensitive) 25% and Ampicillin (Intermediate sensitive) 18.8%. Almost half (47.3%) of the patients received antibiotic during pre admission period whereas 7 (43.8%) of the culture positive patients received pre admission antibiotics. At the end, we can conclude that knowledge of antibiotic sensitivity may have beneficial effect in successful treatment of typhoid fever in children.Unnecessary uses of antibiotic can hinder such sensitivity pattern,
Authors and Affiliations
Dr. Zabeen Choudhury, Dr. Muhammad Jabed- Bin- Amin Chowdhury, Dr A. M. M Minhazur Rahman
Keywords
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