Antibiotic susceptibility pattern of bacterial strains isolated from children with upper respiratory tract infection
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Introduction:Paediatric respiratory tract infections are among the most common reasons for attending hospital and are associated with significant morbidity and mortality. The most infections are limited to the upper respiratory tract and only 5% involve the lower respiratory tract. Definitive bacteriological diagnosis and susceptibility testing would therefore be required for effective management.Objective: To determine the antimicrobial susceptibility pattern of bacterial pathogens isolated from upper respiratory tract infection of children. Methodology: The study was conducted in the Department of Microbiology, Malda Medical College, Malda. A total of 250 clinically diagnosed cases of upper respiratory tract infections (URTI) in children were included in the present study.Throat swab samples were collected from each patient and processed. Following culture, the isolated organisms were identified and antimicrobial sensitivity was performed by standard method.Results: Out of 250 throat swab sample, 226 (90.4%) samples were culture positive for potential pathogens. Predominant isolates were Staphylococcus aureus (42.04%), followed by Streptococcus pyogenes (23.45%), Klebsiellapneumoniae (18.58%), Streptococcus pneumoniae (12.83%) and Pseudomonas aeruginosa (3.10%). Antimicrobial susceptibility tests were performed by Kirby Bauer disc diffusion method. The commercially available antibiotic discs were used. Most of the isolates were susceptible to Amikacin, Gentamycin, Ciprofloxacin, Levofloxacin, Ceftriaxone and Meropenem. Conclusion: The antibiogram will help as guideline for the treatment of such infections. Periodic antimicrobial surveillances are needed to regularly update the guidelines on proper empiric and organism specific antibiotic treatment.
Authors and Affiliations
Dr. Arnab Kumar Mandal, Dr. Tapati Mondal, Dr. Puranjay Saha, Prof. Pratip Kumar Kundu
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