Antibiotic Susceptibility Profile of E. coli Serotype 0157:H7 in ABUTH, Zaria, Nigeria
Journal Title: International Journal of TROPICAL DISEASE & Health - Year 2016, Vol 11, Issue 1
Abstract
The emergence and re-emergence of new strains of microorganisms with high virulent traits and resistant to even new generation antibiotics are significant limiting factor to patients’ recovery in clinical settings. This has indeed created a lot of economic burdens and loss of productive activities at work places especially in developing countries. This study was conducted to evaluate the presence of E. coli serotype O157:H7 in Zaria metropolis and the antibiotics resistance pattern of the isolates. Out of the 150 samples submitted for bacteriological diagnosis at the Medical Microbiology Laboratory of Ahmadu Bello University Teaching Hospital (ABUTH), Shika, Zaria, Nigeria, for the period of 6months (March - August, 2011), 60% of the isolates obtained were identified as E. coli. The incidence of E. coli serotype O157:H7 was 36.7% while the antibiotic susceptibility profile of the isolates to 14 antibiotic commonly prescribed at ABUTH showed that the isolates were 70% resistant to Ceftazidine, 60% to Tetracycline, Ampicillin-Sulbactam, Amoxicillin-Clavulanic acid, 40% to Amoxicillin, Cefuroxime, Nalidixic acid and Cefalexin, 30% to Nitrofurantoin, 20% to Ofloxacin, Chloramphenicol and Ciprofloxacin, 10% to Ceftriaxone and all the isolates were sensitive to Gentamicin. We conclude that there is an incidence of E. coli serotype O157:H7 with varying resistant pattern in Zaria metropolis which has influenced the results obtained from clinical samples in ABUTH. This calls for significant antibiotic surveillance and good hygiene practices to prevent food/water born outbreak of diarrhea associated with E. coli serotype O157:H7, as the identified serotype has been implicated in several deaths around the globe.
Authors and Affiliations
J. C. Igwe, J. A. Onaolapo, J. O. Ehimidu, R. O. Bolaji, A. B. Tytler, B. O. Ojiego, M. Kachallah, N. C. Okafo, A. Musa, M. T. Sidi, M. S. Salihu
Keywords
Related Articles
- EP ID EP328895
- DOI 10.9734/IJTDH/2016/13112
- Views 57
- Downloads 0
Nasopharyngyeal Carriage and Antimicrobial Susceptibility of Streptococcus pneumoniae, in Children under Five Years at Mbarara Regional Referral Hospital, Uganda
Background: Acute respiratory infections (ARI) are a leading cause of childhood morbidity and mortality, causing 25-30% of all deaths in developing countries. Pneumococcal disease is a significant public health problem t...
In vitro and In vivo Evaluation of Antileishmanial Activity of Phyllanthus niruri (Family: Euphorbiaceae)
Aim: The current study was aimed at evaluating the in vitro and in vivo leishmanicidal activity of Phyllanthus niruri against Leishmania donovani. Methodology: The present study was designed to assess in vitro antileishm...
A Comparison of the Accuracy of the Use of Last Menstrual Period and Symphysio-Fundal Height for Gestational Age Determination among Nigerian Women
Aims: The aim of the study was to evaluate the accuracy of the symphysio-fundal height (SFH) in comparison to the last menstrual period (LMP) for gestational age assessment. Study Design: Hospital-based prospective cross...
Hepatitis B Serological Markers and Risk Factors among Pregnant Women and Prospective Blood Donors in Southwestern Nigeria
Background: Hepatitis B control, especially among pregnant women and prospective blood donors, in the developing world is still a disease that must be given attention considering its mortality and morbidity rates. Metho...
A Critical Appraisal of Hearing Impairment among Primary School Children in Port Harcourt, Nigeria
Background: Hearing impairment is the most frequent sensory deficit in human populations affecting over 250 million people in the world. Undetected hearing impairment among primary school children has been linked with po...