Antidermatophytic Activities of Musa sapientum Methanol Leaf Extract in-vitro
Journal Title: Microbiology Research Journal International - Year 2015, Vol 10, Issue 1
Abstract
Aim: The in vitro antidermatophytic activity of methanol leaf extract of Musa sapientum (MSL) against Microsporum canis, Trichophyton tonsurans and Trichophyton rubrum was investigated. Methodology: The methanol leaf extract M. sapientum was obtained by cold extraction. The antifungal activity of the extract was assayed using agar well diffusion techniques. The time-kill antibacterial kinetics of the extract was assessed against one strain of M. canis and two strains of T. tonsurans by plate count technique. Results: The extract had minimum fungicidal concentration (MFC) and minimum inhibitory concentration (MIC) values ranging from 0.0625 mg/ml to 0.5 mg/ml. The least MIC and MFC value was 0.0625 mg/ml against M. canis while T. tonsurans showed the highest MIC and MFC value of 0.5 mg/ml. The extract had no inhibitory or fungicidal effect against T. rubrum. Time-kill kinetic study indicated that the extract exhibited bacteriostatic and bacteriocidal effects against Microsporum canis and Trichophyton tonsurans. Conclusion: The results obtained suggest that the methanol leaf extract of Musa sapientum possesses antidermatophytic properties.
Authors and Affiliations
A. O. Ige, O. O. Mebude, B. A. Adeniyi, E. O. Adewoye
Keywords
Related Articles
- EP ID EP354350
- DOI 10.9734/BMRJ/2015/19261
- Views 66
- Downloads 0
Sequence Variations of Human Papillomavirus Type 16 E6 and E7 Genes in Cervical Cancer Isolates from Gabon
Aims: HPV-16 variants distribution is reported to differ geographically and in their oncogenic potential for progression to cervical cancer. In this study, we investigated the HPV 16 variants distribution among women fro...
Pathogenesis of the Influenza Virus in Diabetes Model Mice
When diabetes model mice and control mice were intranasally infected with the influenza virus (1 LD50), a significant higher mortality rate was observed in the diabetes model. The mortality rate became 100% at 10 days po...
Multidrug Resistance Phenotype and Plasmid Profiling of Escherichia coli Isolates Causing Urinary Tract Infections in North East Part of Bangladesh
Aim: Urinary tract infections (UTIs) caused by Escherichia coli have become a significant worldwide public health concern and the situation is now worsening by the ability of bacteria to develop resistance to antimicrobi...
Effect of Pre-treatment Methods on the Quality Characteristics of Stored Irvingia kernel
Aims: To evaluate effects of pre-treatment methods on the keeping quality of stored Irvingia kernels using ethanol and Ash from palm fronds as preservative agents. Study Design: Study of the microbial isolation using sab...
Strain Development of Aspergillus brasiliensis Using Physical and Chemicals Mutagenesis for Possible Overproduction of Xylanase, Amylase, Protease and Cellulase under Submerged Fermentation (SmF)
Aims: Xylanase is commonly involved in the complete hydrolysis of xylan which consisted of hemicelluloses and celluloses as important components of plant cell wall. This enzyme is essential in wide range of applications...