Antidermatophytic Activities of Musa sapientum Methanol Leaf Extract in-vitro
Journal Title: Microbiology Research Journal International - Year 2015, Vol 10, Issue 1
Abstract
Aim: The in vitro antidermatophytic activity of methanol leaf extract of Musa sapientum (MSL) against Microsporum canis, Trichophyton tonsurans and Trichophyton rubrum was investigated. Methodology: The methanol leaf extract M. sapientum was obtained by cold extraction. The antifungal activity of the extract was assayed using agar well diffusion techniques. The time-kill antibacterial kinetics of the extract was assessed against one strain of M. canis and two strains of T. tonsurans by plate count technique. Results: The extract had minimum fungicidal concentration (MFC) and minimum inhibitory concentration (MIC) values ranging from 0.0625 mg/ml to 0.5 mg/ml. The least MIC and MFC value was 0.0625 mg/ml against M. canis while T. tonsurans showed the highest MIC and MFC value of 0.5 mg/ml. The extract had no inhibitory or fungicidal effect against T. rubrum. Time-kill kinetic study indicated that the extract exhibited bacteriostatic and bacteriocidal effects against Microsporum canis and Trichophyton tonsurans. Conclusion: The results obtained suggest that the methanol leaf extract of Musa sapientum possesses antidermatophytic properties.
Authors and Affiliations
A. O. Ige, O. O. Mebude, B. A. Adeniyi, E. O. Adewoye
Keywords
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- EP ID EP354350
- DOI 10.9734/BMRJ/2015/19261
- Views 70
- Downloads 0
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