Antifungal Effect of Flavonoid 5, 7, 4’-Trimethoxyflavone against Candida krusei Strains
Journal Title: International Journal of TROPICAL DISEASE & Health - Year 2015, Vol 5, Issue 2
Abstract
Most of the flavonoids are considered as constitutive antimicrobial ingredients, especially those belonging to prenylated flavonoids, flavones and isoflavones. In the study, the flavonoid 5,7,4’-trimethoxyflavone was evaluated for its antifungal effects. Four fungal strains were used in the study for activities, Candida krusei – LM 9700, Candida krusei – LM 656, Candida krusei– LM 13 and Candida krusei – LM08. All the microorganism strains were obtained from the Laboratory of Mycology collection. Microdilution method was used for antifungal assay of the flavonoid. The results were also compared with the standard drug, Nistatin (100 UI/mL). The obtained results showed activity fungistatic against Candida krusei strains.
Authors and Affiliations
Abrahão Alves de Oliveira Filho, Heloísa Mara Batista Fernandes, Janiere Pereira de Sousa, Gabriela Lemos de Azevedo Maia, José Maria Barbosa Filho, Thais Josy Castro Freire de Assis, Hilzeth Luna Freire Pêssoa, Edeltrudes Oliveira Lima
Keywords
Related Articles
- EP ID EP343350
- DOI 10.9734/IJTDH/2015/14060
- Views 65
- Downloads 0
Evaluation of Fine Needle Aspiration Cytology Technique for Early Diagnosis of Tubercular Lymphadenitis in Patients Presenting at a
Aims: The aim of the present study is to evaluate whether FNAC helps in detecting tubercular lymphadenitis (TB LAN) at an early stage in a primary care setting. Demographic and cytomorphological profile of TB LAN in this...
Urban–Rural Disparities and Determinants of Nutritional Status of Under-Five Children: An Example of Akinyele Local Government Area, Ibadan
Background: Nutrition is an important element of a child’s survival and development. To achieve MDG 4 in Nigeria, nutritional status of under-five children needs to be improved as malnutrition remains an underlying facto...
Epidemiology of Hepatitis C Virus Infection in Egypt
Hepatitis C virus constitutes an epidemic in Egypt having the highest prevalence in the world of 14.7%. The reasons behind this unique epidemic may be dated back to iatrogenic role of parenteral antischistosomal therapy...
Influence of Substituents on the Antiplasmodial and Cytotoxic Activities of 5-chloro-3,4-dihydro-1H-pyrano[3,4-b]-1,10-phenanthrolinone as Antimalarial Agent
Background: Malaria is one of the most common parasitic disease in tropical and subtropical regions. Plasmodium falciparum, one of the causative agent of malaria is resistant to many type of antimalarial drugs. This stud...
Heavy Metal Contamination of Herbal Drugs: Implication for Human Health-A Review
Interest in the use of medicinal plants in treatment of diseases in Africa has increased tremendously over the past decade. Ingestion of contaminated medicinal plants and herbal medicinal products is regarded as potentia...