Antifungal Effect on Candida Albicans of Laurel, Coconut and Coriander Seed Oil
Journal Title: Open Access Journal of Pharmaceutical Research - Year 2019, Vol 3, Issue 3
Abstract
Candida albicans (C.P. Robin) mushroom has the highest pathogenicity among other candida species. The high amounts of linoleic acid (18:2), and oleic acid (C 18: 1, 9 octadecenoic acid) in the biphasic mutant fungus Candida albicans in vitro by using cold press method from Laurel and Coriander seeds, and (-)-isopulegol monoterpen component were cultured in the microbiology laboratory of the ZadeVital R&D center. Kirby-Bauer disc diffusion method was used in the passages. The proportions of fatty acids were measured by GC (Gas Chromatography), and the free fatty acids by GC MS (Gas Chromatogram-Mass Spectrometry). The oils extracted from the bay and coriander seeds by cold pressing were absorbed into sterile antibiotic discs. Nystatin antibiotic was used as a reference. Antibiograms were checked every 2 days for 24 hours. The zones formed in the passages were measured in mm and resistance and sensitivity analyzes were performed against Candida albicans strain oils. We have found that (-)-isopulegol monotherpen is a determinant of antifungal properties compared to other fatty acids. In this study, we have seen that oils extracted by cold pressing from laurel and coriander seeds have topical antifungal properties on Candida albicans species.
Authors and Affiliations
Cansel C*, Huseyin HD, Seyma AB, Ali G, Sidika BO, Yasemin G, Beril K, Hale Feyza B and Mevlut B
Keywords
Related Articles
- EP ID EP746282
- DOI 10.23880/oajpr-16000179
- Views 40
- Downloads 0
A Review on Cucurbitaceae
Plants are basic source of food and energy cucurbitaceous family possess antibacterial, antimicrobial, antifungal characteristics and showed activities like antioxidant, phytochemical and hypoglycaemic activity. Cucurbi...
Detonation Nanodiamonds: Opportunity for Pharmaceutical and Medical Application
Detonation nanodiamonds have 4-5 nm size primary particles, stable inert core, high surface area and tunable surface structures. They are very attractive from pharmaceutical point of view as a drug delivery vehicle. Nitr...
Evaluation of Anti-inflammatory Activity of Clerodendrum wallichii (Merr.) Leaves
Clerodendrum wallichii Merr. (Family: Verbenaceae) commonly known as Sampulis is native to Southern Asia from the Himalayas to Southern China, the Nicobar Islands and Northeast into Pakistan. In India, it is mainly foun...
Galenic Laboratory: State of the Art-A Scientific and Technological Discipline, Innovation and Management
The term galenic imply a scientific and technical matter but also an art. Related the hospital practice the future of pharmacy pass though the innovation of the galenic lab. Observing the today hospital practice HP in m...
Carbohydrates Test and In Vitro Inhibitory Activities of AlphaGlucosidase and Alpha-Amylase of Stem Bark Extracts of Musanga Cecropioides
Elevated postprandial hyperglycemia is one of the risk factors linked to diabetes. Decreasing postprandial hyperglycemia is possible by inhibiting certain carbohydrate hydrolyzing enzymes like α-amylase and α-glucosidase...