Antifungal immunity in selected fungal infections
Journal Title: Advances in Hygiene and Experimental Medicine - Year 2015, Vol 69, Issue 0
Abstract
Fungi are omnipresent in the environment; hence they are frequent factors causing infections in humans and animals even if their immune system works correctly. These facts stimulated interest in and the will to understand the antifungal immunity mechanisms. It has been, however, evidenced that the immunological response to mycotic pathogens is related to the species and morphological form of the fungus. Nevertheless, it is assumed that always in the antifungal response, there are mechanisms of innate and adaptive immunity that cooperate with one another to eliminate such pathogens. It has been evidenced that the main elements of antifungal immunity are physical barriers of the organism, phagocytosis, cytotoxicity, and possibly trogocytosis of PMN and MN cells, as well as T-cells, and to a smaller extent B-cells, the proportion of which is principally related to their products activating the processes of PMN and MN cells. An important role in this immunity also belongs to PRR, which activate the main processes of phagocytosis and cytotoxicity of PMN, MN, NK and DC cells.
Authors and Affiliations
Alicja Trzeciak-Ryczek, Beata Tokarz-Deptuła, Wiesław Deptuła
Keywords
Related Articles
- EP ID EP67663
- DOI -
- Views 166
- Downloads 0
EGFR and Bcl-2 in gastric mucosa of children infected with Helicobacter pylori
Aim: The aim of the study was to evaluate the expression of EGFR and Bcl-2 proteins as inhibitory markers of apoptosis in surface epithelial cells and gland cells of antral gastric mucosa in children infected with Helico...
Muscle activity in the course of rehabilitation of masticatory motor system functional disorders
On the basis of selected cases, evaluation of the usefulness of muscular exercises in rehabilitation of patients stricken by a dysfunction of the motor system of the chewing organ was accomplished. The assessment of the...
Zaburzenia metaboliczne i stan odżywienia w autoimmunologicznych chorobach tarczycy
Nutrigenomics – bioactive dietary components
Nutrigenomics analyzes relations between diet and genes, and identifies mechanisms in which food and nutrition affect health and lifestyles and noncommunicable diseases (R. Chadwick, 2004). Bioactive dietary components a...
Effect of allograft inflammatory factor-1 gene polymorphisms on rheumatoid arthritis treatment with methotrexate
Objective: Methotrexate (MTX) in low doses is used in the therapy of rheumatoid arthritis (RA). The aim of many studies is to identify factors predicting the outcome of treatment with methotrexate in rheumatoid arthritis...