Antihyperglycemic and hypoglycemic effect of portulaca quadrifida linn
Journal Title: International Journal of Allied Medical Sciences and Clinical Research - Year 2016, Vol 4, Issue 4
Abstract
The hypoglycemic effect of ethanolic extract of Portulaca quadrifida was investigated on glucose loaded and streptozotocin induced diabetic rats. The blood glucose levels were measured at 0, 1, 2 and 3 h after the treatment. The ethanolic extract of P. quadrifida (200 mg/kg) reduced the blood glucose of normal rat from 85.331.79 to 65.173.67 mg/dl, 3 h after oral administration of the extract (P<0.001). It also significantly lowered blood glucose level in streptozotocin induced diabetic rat from 330.673.27 to 132.174.49 mg/dl, 3 h after oral administration of the extract (P<0.001). The antihyperglycemic activity of P. quadrifida was compared with tolbutamide, an oral hypoglycemic agent.
Authors and Affiliations
Vijayarangan Sivasamy
Keywords
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