Antimicrobal and ostheointegration activity of bone cement contains nanometals
Journal Title: Journal of Achievements in Materials and Manufacturing Engineering - Year 2016, Vol 74, Issue 1
Abstract
Purpose: One of the major problems in bone surgery are infections – especially thoseoccurring in the course of the operating on the patients with lowered immunity system,because they carry the danger of complications. In the Mechanical Department of TechnicalUniversity of Gdansk, there has been carried the research with the use of bone cement andmetal nanoparticles.Design/methodology/approach: The bone cement was used without supplement orwith one or two drugs. These experiments are the latest, because include pure bone cement(without drugs) with nanometals. The titanium specimens was covering with such composecoating. The implant was inserted into rat`s thigh for six weeks. Afterwards the implantwas removed from the body and examined by means of scanning electron microscope.Simultanously biological research was carried out. Bonless samples were placed intobacterial liquid, generated by the researcher (the Patent number P 409082 ) containing fivemost frequently occurring bacteria in human body.Findings: Result of the SEM research was positive – there was good adhesion ofostheoblasts to the surface and there were no traces of infection.Practical implications: The research concerns bone cement with nanoparticles proves,that nanoparticles are the alternatives to antibiotics.
Authors and Affiliations
B. Świeczko-Żurek
Keywords
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