Antimicrobial activity of Ficus sycomorus L. (Moraceae) leaf and stem-bark extracts against multidrug resistant human pathogens
Journal Title: Herba Polonica - Year 2015, Vol 61, Issue 1
Abstract
The present work was conducted to investigate antibacterial activity of methanol and acetone in leaf (LE) and stem-bark (SBE) of Ficus sycomorus L. crude extracts against sensitive and resistant species of Staphylococcus aureus and Acinetobacter baumannii pathogens. Antimicrobial activity expressed by disc-diffusion method (zone of inhibitions – ZIs), minimum inhibitory concentrations (MICs) and minimum bactericidal concentration (MBC) were measured as reported for many investigations. Similar study with 6 commercial antibiotics as a reference drug was undertaken. Based upon the estimated ZIs, MIC and MBC values, acetone LE exhibited higher antimicrobial activity than that of methanol one. Otherwise, standard antibiotics have lower effectiveness (ZIs, MICs and MBC) on all tested bacteria as compared to the SBE and LE. The highest antibacterial activity was recorded in sensitive A. baumannii isolate with MICs 2.5, 4.9 mg/ml and MBC 3.8, 9.7 mg/ml for acetone LE and SBE, respectively. Our data indicated that the lowest antibiotics antibacterial activity was recorded for resistant A. baumannii pathogen. It was lower than those of the both plant fractions extracts.
Authors and Affiliations
Basel Saleh, Razan Hammoud, Ayman Al-Mariri
Keywords
Related Articles
- EP ID EP266805
- DOI 10.1515/hepo-2015-0009
- Views 69
- Downloads 0
Antimicrobial activity of Capparis spinosa as its usages in traditional medicine
Capparis spinosa roots and fruits are traditionally used for the treatment of diseases such as diarrhea and hemorrhoids. In the 10th century, farmers also used aqueous extract from its roots for disinfecting their plants...
Activity of essential oils against Staphylococcus aureus strains isolated from skin lesions in the course of staphylococcal skin infections
Introduction: Staphylococcus aureus is an important etiological agent of skin and soft tissue infections. Due to the increasing resistance of this bacterium to antimicrobial agents, treatment of staphylococcal infections...
Accumulation of phenolic compounds in the purple betony herb (Stachys officinalis L.) originated from cultivation
Introduction: Purple betony (Stachys officinalis L., Lamiaceae) is a perennial of versatile medicinal usage. Nowadays, in Poland betony herb is collected exclusively from wild growing plants. Decreasing number of its nat...
Morphological and pharmacokinetic properties of oral solid dietary supplements containing plant extracts
Introduction: Dietary supplements are a good way to supplement the deficiency of certain micronutrients and organic components (therapeutic agents) in human body. They are most often available in concentrated form as tab...
Solubility and solubilizing capabilities of aqueous solutions of Extractum Taraxaci e radix cum herba aqu. siccum in light of selected values of general Hildebrand-Scatchard-Fedors theory of solubility
Introduction: The general Hildebrand-Scatchard theory of solubility supplemented by Fedors’ solubility parameter was used to estimate the real solubility by -log x2 (log of the mole fraction) of phytochemicals contained...