Antimicrobial Activity of Hydrogen Peroxide, Sesame and Gum Arabic against Streptococcus Mutans
Journal Title: International Journal of Health Sciences and Research - Year 2017, Vol 7, Issue 1
Abstract
Background: Dental caries is one of the most common and costly diseases in the world and causes the tooth loss in adults by cariogenic microorganism and food debris, affecting more than 90% of the population, regardless of age, sex or race. One of the strategies for preventing the caries is inhibition of bacterial growth specially S. mutans and prevention of microbial colonization. Objective and Methods: The present study was conducted to isolate, identify, studying the effect of sesame, gum Arabic (GA) and hydrogen peroxide (H2O2) against S.mutans in vitroand determination of minimum inhibitory concentrations (MIC) by using well diffusion method. Results: We isolated 33 Streptococcus sp which were identified by morphological, biochemical characteristics and conformed by VITEK 2 system (version: 07,01) to 27.4, 24.3, 18.3, 12, 9, 6, 3% of S. mutans, S. salivaries, S. mitis,S. sanguinis, S. downei, S.oralis and S. pneumonia respectively. The H2O2 was highly active compound against S. mutans gave 24.0 + 0.1. On the other hand, sesame and GA gave the moderate inhibition activity 20.0+0.2 and 17.0 + 0.8 against S. mutans, respectively. The MICs of GA, sesame oil and H2O2 were used by agar well diffusion method against S. mutans gave 5 mg/ml for both GA and sesame, while gave 1.9% for H2O2. Conclusion: The present research is a preliminary attempt to investigate the antibacterial activity against S. mutans. Based on the results of the present research, the sesame, GA and H2O2 can be used in toothpaste and medicine for the treatment of dental caries. However, further research is needed to identify and characterize the active molecules in sesame and GA responsible for their antimicrobial properties and to determine its potential for use in pharmaceutical manufacture.
Authors and Affiliations
Muataz Mohammed Banjar
Keywords
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