Antimicrobial Activity of Penicillin G and N-acetylcystein on Planktonic and Sessile Cells of Streptococcus suis
Journal Title: Polish Journal of Microbiology - Year 2016, Vol 65, Issue 1
Abstract
The aim of this study was to investigate the capacity of [i]Streptococcus suis [/i]strains to form biofilms and to evaluate the antimicrobial activity of Penicillin G and N-acetylcystein (NAC) on both [i]S. suis[/i] sessile and planktonic forms. Only non-typeable isolates of [i]S. suis[/i] were correlated with a greater biofilm formation capacity. The MCI of Penicillin G and NAC required for inhibiting biofilm growth were higher than the required concentration for inhibiting planktonic growth. The combinations of NAC and Penicillin G showed a strong synergistic activity that inhibited biofilm formation and disrupted the pre-formed biofilm of [i]S. suis[/i].
Authors and Affiliations
Ivette Espinosa, Michel Báez, Evelyn Lobo , Siomara Martínez, Marcelo Gottschalk
Keywords
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