Antimicrobial Activity of solvent Extracts of Selected Red Sea Macroalgae against Some Pathogenic Microorganisms
Journal Title: Saudi Journal of Pathology and Microbiology - Year 2018, Vol 3, Issue 3
Abstract
Abstract:This study was carried out to evaluate the antimicrobial activity of hexane, chloroform, ethyl acetate and water extracts of six marine macroalgaebelonging to different families namely green algae (Chlorophyceae), brown algae (Phaeophyceae) and the red algae (Rhodophyceae) collected from the intertidal area of the Sudanese Red Sea coast near Port Sudan. Successive extraction techniques using hexane, chloroform, ethyl acetate and waterwere used for extracting theactive principlesof the algae and the disc-diffusion method was performed to examine the activity of the crude extracts against four pathogenic bacteria and one fungus. Most of the tested algal extracts exhibited considerable bioactivity and inhibited the growth of most of pathogenic microorganisms under investigation. The chloroform extract of the red alga Gracillariaspproduced a maximum inhibition zone of 22 mm against Escherichia coli whereas the chloroform extract of the red alga Laurenciapapillosa showed a low antimicrobialactivity with a minimum inhibition zone of 5 mm against Bacillus subtilis. Some extracts had no antimicrobial activity against the tested pathogens. The tested algal extracts did not show any different antimicrobial effects on the selected microorganisms when considered as Gram-positive or Gram-negative bacteria, however the fungal sample tested was less sensitive when compared with the bacterial samples. The results showed that chloroform and ethyl acetate were the appropriate solvents for extracting the bio-active agents. The study demonstrated clearly that the tested marine macroalgae from Sudanese Red Sea coast represent a potential and alternative source of secondary metabolites with antimicrobial activity. Keywords: Algal extracts, Antimicrobial activity, Pathogens, Red Sea, Sudan.
Authors and Affiliations
Ehab Omer Abdalla, Mohammed TahaAbdalla Shigidi, Hassan Elsubki Khalid
Keywords
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