Antimicrobial Activity of solvent Extracts of Selected Red Sea Macroalgae against Some Pathogenic Microorganisms
Journal Title: Saudi Journal of Pathology and Microbiology - Year 2018, Vol 3, Issue 3
Abstract
Abstract:This study was carried out to evaluate the antimicrobial activity of hexane, chloroform, ethyl acetate and water extracts of six marine macroalgaebelonging to different families namely green algae (Chlorophyceae), brown algae (Phaeophyceae) and the red algae (Rhodophyceae) collected from the intertidal area of the Sudanese Red Sea coast near Port Sudan. Successive extraction techniques using hexane, chloroform, ethyl acetate and waterwere used for extracting theactive principlesof the algae and the disc-diffusion method was performed to examine the activity of the crude extracts against four pathogenic bacteria and one fungus. Most of the tested algal extracts exhibited considerable bioactivity and inhibited the growth of most of pathogenic microorganisms under investigation. The chloroform extract of the red alga Gracillariaspproduced a maximum inhibition zone of 22 mm against Escherichia coli whereas the chloroform extract of the red alga Laurenciapapillosa showed a low antimicrobialactivity with a minimum inhibition zone of 5 mm against Bacillus subtilis. Some extracts had no antimicrobial activity against the tested pathogens. The tested algal extracts did not show any different antimicrobial effects on the selected microorganisms when considered as Gram-positive or Gram-negative bacteria, however the fungal sample tested was less sensitive when compared with the bacterial samples. The results showed that chloroform and ethyl acetate were the appropriate solvents for extracting the bio-active agents. The study demonstrated clearly that the tested marine macroalgae from Sudanese Red Sea coast represent a potential and alternative source of secondary metabolites with antimicrobial activity. Keywords: Algal extracts, Antimicrobial activity, Pathogens, Red Sea, Sudan.
Authors and Affiliations
Ehab Omer Abdalla, Mohammed TahaAbdalla Shigidi, Hassan Elsubki Khalid
Keywords
Related Articles
- EP ID EP399434
- DOI -
- Views 69
- Downloads 0
Cardiac Troponin I and CK-MB in Diagnosis of Acute Coronary Syndrome in Patents without ST Elevation
Abstract: There is uncertainty as to the comparative prognostic value between cardiac troponin I (cTnI) and CK-MB in acute coronary syndrome (ACS). The objective is to compare the prognostic value between cTnI and CK-MB...
A Comparative Study - Manual Method against Automated Peripheral Smear Preparation
Abstract:A blood film or peripheral blood smear is a thin layer of blood smeared on a microscope slide and then stained in such a way to allow the various blood cells to be examined microscopically. This can be done by m...
Genotypic and Phenotypic Drug Resistance of Bacteria Associated with Diabetic Septic Foot Infections among Sudanese
Abstract: Diabetes mellitus (DM) is one of the main problems in health systems and a global public health threat that has increased dramatically over the past two decades. According to epidemiological studies, the number...
Positive Rheumatoid Arthritis in Antisynthetase Syndrome
Positive AnticyclicCitrullinatedPeptid Antibody in the antisynthetase syndrome should not lead to systematic diagnosis of association Antisynthetase syndrome-Rheumatoid arthritis. However their positivity is a marker of...
Cytopathological Study of Non Neoplastic Lesion in Cervix at Birat Medical College Teaching Hospital Nepal
Abstract:Like in other developing countries non –neoplastic region of cervix in Pap smear is most common findings. In Nepal cervical pap-smear screening is not done my most of woman due to lack of awareness. The objectiv...