ANTIMICROBIAL ACTIVITY OF THE ETHANOLIC AND AQUEOUS EXTRACT OF PASSION FRUIT (PASSIFLORA EDULIS SIMS), IN THE ABSENCE AND PRESENCE OF Zn(OAc)2.2H2O.
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2017, Vol 6, Issue 9
Abstract
The aqueous and ethanolic extract of mature passion fruit in the absence and presence of transition metal salts were subjected to antimicrobial studies using the Disc Diffusion Assay under aseptic conditions. From the ethanolic extract, a white solid crystallised out and its antimicrobial activity was investigated. The highest AZOI of 268.7 mm2 was induced by sample 9 against S. aureus. The lowest AZOI of 21.6 mm2 was induced by sample 6 against C. albicans. These quoted AZOI are exclusive of the reference AZOI. For the non-metal solution, the highest AZOI of inhibition was induced by the aqueous solution (0.026g/ml) against P. aeruginosa i.e P. aeruginosa was more susceptible. There seems to be an increased in antimicrobial activity of the ethanolic fruit extract as the concentration increases. For the aqueous extract of the white isolate, an increase in concentration generally resulted in a decrease in antimicrobial potency. Interestingly, there seems to be an increase in antimicrobial activity of the aqueous solution of the white ethanolic isolate in the presence of Zn (OAc).2H2O salt against pathogens in some cases and a decrease in another instance. Selective antimicrobial activity was observed for the fruit extracts in the presence and absence of Zn(OAc)2.2H2O. For all experiments conducted, antimicrobial activity seems to be less than that of the standard antibiotics: Ampicillin and Nystatin.
Authors and Affiliations
Dr. R. C. Jagessar
Keywords
Related Articles
- EP ID EP618649
- DOI -
- Views 173
- Downloads 0
EVALUATION OF THE EFFICACY OF CLEANING AND DISINFECTION IN BROILER FARMS BETWEEN REST PERIODS IN KHARTOUM STATE, SUDAN.
This study was carried out during the period from November 2015 to November 2017 in Bahri locality, Sudan. The objectives of the study were to determine the efficacy of cleaning and disinfection of broiler farms between...
EXPLORING ANTI-HYPERGLYCEMIC POTENTIAL OF ALKALOID COMPOUNDS FROM CATHARANTHUS ROSEUS G. DON (L) AGAINST VARIOUS TYPE II DIABETES TARGETS BY IN SILICO VIRTUAL SCREENING
Background: Catharanthus roseus (L.) G. Don (C. roseus) is a prominent anticancer herb having high alkaloid content. Besides known anticancer effect, this plant has been also traditionally used as an effective anti-diabe...
EXTRACTION AND DETERMINATION OF ANTHOCYANIN PIGMENT FROM HIBISCUS SABDARIFFA CALYX BY THE USE OF UV AND HPTLC METHOD
Objective: Extraction and determination of anthocyanin pigment from Hibiscus sabdariffa calyx. Method: Calyces were dried, powdered and extracted with ethanolic solvent acidified with citric acid. The extract then was ex...
APPLICATION OF RESVERATROL-LOADED CUBIC LIQUID CRYSTAL NANOPARTICLES
Based on previous studies on the preparation and characterization of resveratrol-loaded cubic liquid crystalline nanoparticles (RESCLCNPs), in this article, we investigated the antitumor activity of RES-CLCNPs. Its effec...
ASSESSMENT OF HEALTH RELATED QUALITY OF LIFE IN LIVER DISEASE PATIENTS REVIEW ARTICLE
Health-related quality of life has become an important outcome measure for overall assessment of patients with liver disease; it provides detail about the nature of disease and extent of its effects on individuals. Actua...