ANTIMICROBIAL ACTIVITY OF WHOLE FRUITING BODIES OF TRAMETES HIRSUTA (WULF. FR.) PIL. AGAINST SOME COMMON PATHOGENIC BACTERIA AND FUNGUS
Journal Title: International Journal of Pharmaceutical Sciences and Drug Research - Year 2011, Vol 3, Issue 3
Abstract
Aqueous and methanolic extracts of fruit bodies of Trametes hirsuta were tested against five pathogenic fungi like Penicillium sps., Aspergillus fumigatous, Aspergillus niger, Aspergillus flavus and Mucour indicus and five bacterial stains such as Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus, and Streptococcus mutans. The antibacterial and antifungal activities of all these extracts were demonstrated by well diffusion assay. Nearly all the extracts were found effective against these bacterial and fungal strains. The minimum inhibitory concentration of the various extract range from 200 mg to 50 mg on tested bacteria and fungi. The maximum antibacterial activity of aqueous extract of whole fruit bodies of Trametes hirsuta was found 33 mm at 200 mg against Staphylococcus aureus than that of methanol extract. The significant antifungal activity of aqueous extract was found 46 mm at 200 mg against Aspergillus flavus than that of methanol extract. The antimicrobial activity was showed at concentration dependent.
Authors and Affiliations
E. Sivaprakasam, D. Kavitha, R. Balakumar, S. Sridhar, J. Suresh Kumar
Keywords
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