Abstract

[i]Background[/i]: The optimal choice of antimicrobial therapy is an important problem in hospital environment in which the selection of resistant and virulent strains easy occurs. S. aureus and especially MRSA (methicillin-resistant S. aureus) creates difficulties in both treatment and prevention of nosocomial infections. [i]Aim[/i]: The purpose of this study is to determine the sensitivity and the resistance to chemotherapy of staphylococci strains isolated from various pathological products. [i]Material and Method[/i]: We identified Staphylococccus species after morphological appearance, culture properties, the production of coagulase, hemolisines and the enzyme activity. The susceptibility tests were performed on Mueller-Hinton medium according to CLSI (Clinical and Laboratory Standards Institute). [i]Results[/i]: The strains were: MSSA (methicillin-susceptible S. aureus) (74%), MRSA (8%), MLS B (macrolides, lincosamides and type B streptogramines resistance) (12%) and MRSA and MLS B (6%). MRSA strains were more frequently isolated from sputum. MRSA associated with the MLS B strains were more frequently isolated from pus. MLS B strains were more frequently isolated from sputum and throat secretions. All S. aureus strains were susceptible to vancomycin and teicoplanin. [i]Conclusions[/i]: All staphylococcal infections require resistance testing before treatment. MLS B shows a high prevalence among strains of S. aureus. The association between MLS B and MRSA remains a major problem in Romania.

Authors and Affiliations