ANTIMICROBIAL RESISTANCE PATTERN OF ENTEROCOCCUS SPECIES WITH SPECIAL REFERENCE TO VANCOMYCIN RESISTANCE
Journal Title: International Journal of Microbiology Research - Year 2016, Vol 8, Issue 7
Abstract
Background: Enterococci are an important cause of hospital acquired infection and have become progressively more resistant to antibiotics. Vancomycin resistant enterococci are emerging as an important problem in hospitals worldwide leading to therapeutic failures. Therefore, this study was undertaken to estimate the prevalence of the enterococcus infection in our tertiary care hospital and to determine the antibiogram with special emphasis on vancomycin resistance. Methods: From the period, January 2015-July 2015,225 isolate of enterococcus species were obtained from different clinical samples .The antibiotic susceptibility of these enterococcal isolates was performed by Kirby Bauer Disk Diffusion method and was further confirmed by Vitek 2C System. Results: Out of these 225 enterococcal isolates, 168(74.7%) were identified as Enterococcus fecalis and 51 (22.7%) were Enterococcal faecium. The maximum no of isolates were from urine 122(54.2%) followed by the isolate from pus 41(18.2%). These isolates showed high level resistance to ampicillin, ciprofloxacin and high level gentamycin i.e. 58.2%, 47.6% and 43.6% respectively. The resistance to vancomycin in our study was found in only 10(4.4%) enterococcal isolates. Conclusion: The study showed low level resistance to vancomycin amongst enterococcal isolates. Howeverthe presence of vancomycin resistant enterococci (VRE) along with increased rate of multidrug resistance amongst these isolates calls for regular surveillance of antimicrobial susceptibilities for the enterococcal isolates.
Authors and Affiliations
M. SHARMA, S. JAIN, N. SHREE
Keywords
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