Antimicrobial Susceptibility Patterns of Pseudomonas aeruginosa Clinical Isolates at a Tertiary Care Hospital in Ambajogai
Journal Title: Journal of Microbiology and Related Research - Year 2017, Vol 3, Issue 2
Abstract
Introduction: Currently antibiotic resistance in bacterial populations is one of the greatest challenges to the effective management of infections. Infections caused by Pseudomonas aeruginosa are frequently life threatening & difficult to treat as it exhibits intrinsically high resistance to many antimicrobials & the development of increased, particularly multi-drug resistance in health care settings. Objective: The present study was done to determine the drug sensitivity pattern of Pseudomonas aeruginosa from various clinical specimens in our set up. Materials and Method: This study was conducted during October 2015 to May 2016. A total of 376 strains of Pseudomonas aeruginosa were isolated from various clinical specimens. Pseudomonas aeruginosa was identified by using standard microbiological techniques. Antimicrobial susceptibility patterns of all the isolates were carried out by Kirby- Bauer disk diffusion method as per CLSI guidelines. Result: A total 376 strains of Pseudomonas aeruginosa were isolated of which 267 (71%) were from indoor & 109 (29%) were from outdoor patients. Of the 376 isolates 206 were from males & 170 were from females. Majority of isolates of Pseudomonas aeruginosa were obtained from specimens of pus. Majority of the strains showed low level of susceptibility to Ceftazidime (38%), Ofloxacin (40.4%), Ciprofloxacin (42.1%), Piperacillin (47.7%) & Gentamicin (51%). We got good sensitivity with Tobramycin (82.1%) & with Amikacin (78.3%). All isolates were susceptible to Imipenem (100%). Conclusion: The result of our study suggests the occurrence of resistant strains of Pseudomonas aeruginosa. Periodic susceptibility testing should be carried out over a period of two to three years to detect the resistance trends & judicious, rational treatment regimen prescription should be followed by physician.
Authors and Affiliations
Kokane V. R.
Keywords
Related Articles
- EP ID EP462391
- DOI 10.21088/jmrr.2395.6623.3217.5
- Views 94
- Downloads 0
Prevalence and Antibiotic Sensitivity Pattern of Organisms Isolated from Post Injection Intramuscular Abscesses in a Tertiary Care Hospital, Kashmir
Background: Intramuscular injections are a routine procedure performed in the hospital settings mainly for therapeutic purpose. Improperly performed injections may lead to complications of which abscess formation is the...
Prevalence of Transfusion Transmissible Infections Among Donors in A Tertiary Care Hospital: A Retrospective Study
Introduction: Blood transfusion is associated with several risks which particularly includes Transfusion Transmissible Infections (TTI’s) like Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human Immunodefeciency Viru...
Mycological Profile and Epidemiology of Dermatophytes in A Tertiary Care Hospital
Background: Dermatophytosis is one of the commonest superficial infections encountered in humans. Some of the non-infectious dermatological disorders resemble superficial fungal infections and should be differentiated by...
Speciation and Resistotyping of Coagulase Negative Staphylococci in Clinical Isolates in Kerala Medical College, Palakkad
Introduction: Coagulase negative staphylococci are important causative agents of 10% of pyogenic infections in hospitals, which include a range of infections like surgical wound sepsis, bacteremia, native valve endocardi...
Isolation of MTB Strains and Determining the Antibiotic Susceptibility Pattern via Bactec 320 from the Females of Child Bearing Age
Background: The BACTEC MGIT 320 is a new, lower-capacity instrument for liquid culture developed for the growth and detection of M. tuberculosis and antimicrobial susceptibility testing. MGIT has an improved speed and se...