Antioxidant Activity, Total Phenolic and Flavonoid Contents of Essential Oils of Three Cyperus Species (Cyperaceae)
Journal Title: Journal of Pharmaceutical Research International - Year 2015, Vol 7, Issue 1
Abstract
Aims: To determine the in vitro antioxidant activity, total phenolic and flavonoid contents of essential oils from the rhizomes of Cyperus distans, Cyperus papyrus and Cyperus rotundus collected from different locations. Study Design: The study was design to investigate the total phenolic and flavonoid contents and antioxidant properties of essential oils from the rhizomes of Cyperus distans, Cyperus papyrus and Cyperus rotundus in order to assess their medicinal values. Place and Duration of Study: Fresh plant materials of Cyperus distans, Cyperus papyrus and Cyperus rotundus were randomly collected at the flowering stage between October, 2006 and September, 2007 from different locations in KwaZulu-Natal Province, South Africa. Methodology: The antioxidant potential of the oils of C. distans, C. papyrus and C. rotundus was evaluated by 1,1-diphenylpicryl-hydrazyl (DPPH), hydroxyl radical, nitric oxide, metal chelating and reducing potential methods. The total phenolic and flavonoid contents of the oils were determined by spectrophotometer using Gallic acid and Quercetin equivalents, respectively. Results: The essential oils of C. distans, C. papyrus and C. rotundus showed no metal chelating activity and poor aptitude to scavenge 1,1-diphenyl-2-picrylhydrazyl radical with inhibitory concentration (IC50) >173 µg/mL, when compared to standard antioxidants; butyl hydroxyl anisole (BHA), butyl hydroxyl toluene (BHT), ascorbic acid (Vitamin C) and α-tocopherol with IC50 ≤10.70 µg/ mL. But, displayed significant antioxidant effects, when tested with other methodologies. The total phenolic content and the concentrations of flavonoid in the oils varied from (0.032 to 0.085) mg (Gallic acid)/100 µL and (0.027 to 0.072) mg (Quercetin)/ 100 µL equivalents, respectively. Conclusion: The observed difference in antioxidant activities of the essential oils of C. distans, C. papyrus and C. rotundus may be due to climatic, seasonal and geographic conditions, harvest period, distillation technique, plant maturity and the presence of some major components or synergy between compounds present in the essential oils.
Authors and Affiliations
Oladipupo A. Lawal, Anthony B. Ojekale, Olugbenga S. Oladimeji, Titilola S. Osinaike, Adetayo A. Sanni, Mthokozisi B. C. Simelane, Rebamang A. Mosa, Andy R. Opoku
Keywords
Related Articles
- EP ID EP344282
- DOI 10.9734/BJPR/2015/18631
- Views 70
- Downloads 0
Free Radical Scavenging Activity of the Nigerian Leech (Aliolimnatis michaelseni) Saliva Extract
Introduction: Antioxidant is a substance that is capable of restricting or frustrating the oxidation of other oxidizable molecules by suppressing the free radical- caused oxidation chain reaction. They occur naturally in...
Isolation and Characterization of β-Sitosterol-3-O-β-D-glucoside from the Extract of the Flowers of Viola odorata
Isolation from the ethanol extract of the flowers of Viola odorata resulted in the isolation of β-Sitosterol-β-D-glucoside. This compound has not been previously isolated or reported from the flowers of this variety. The...
Development of Ultrasound Sensitive eLiposomes Containing Doxorubicin for Drug Delivery
Aims: A novel nanocarrier was formulated by remote loading of doxorubicin (Dox) into a dipalmitoylphosphatidylcholine (DPPC) liposome that also contains various perfluorocarbon (PFC) droplets within its aqueous interior....
Pharmacokinetics and Bioequivalence Study of Two Proton Pump Inhibitor Products
Omeprazole (OPZ) efficiently suppresses acid secretion in the parietal cells of the stomach. It is widely recommended as proton pump inhibitor (PPI) in Egypt. Presence of many products containing omeprazole available in...
Review of Drug Interactions: A Comprehensive Update
Prescribing multiple medications predisposes to possibilities of occurrence of drug interactions. Various different terminology and ways exist to classify or arrange drug interactions. Drugs interact with other drugs, fo...