Antioxidant Status in HIV Positive Pregnant Women
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 8
Abstract
Aims and Objectives: Compare the level antioxidant in HIV positive pregnant, normal pregnant and non pregnant women, socioeconomic status and to determine oxidative stress levels in all study groups a) Glutathione (GSH) concentration b) Malondialdehyde (MDA) concentration c) Total Antioxidant Status (TAS) d) Glutathione Peroxidase (GPx) e) Super Oxide Dismutase (SOD) Result and Conclusion: The activity of GR, GPx, SOD, MDA and total antioxidant in non pregnant, normal pregnant and HIV positive pregnant women. The activity in non pregnant women and normal pregnant women were 9.27 ±1.74, 47.30 ± 10.27, 1329.7 ± 111.8, 3.03 ± 0.49, 1.47 ± 0.18 and 4.37 ± 0.79, 27.17 ± 2.76, 944.9 ± 193.1, 4.50 ± 0.32, 1.19 ± 0.20 respectively. And the activity was 3.51 ± 1.15, 19.54 ± 2.51, 675.3 ± 125.9, 5.46 ± 0.55, and 0.88 ± 0.15 found in HIV pregnant women. It shows that the level of antioxidant in HIV pregnant women was significantly decreased but MDA level was slightly increased found compare to non pregnant and normal pregnant women. On the basis of our result we concluded that the HIV positive pregnant women experience more free radical injury than those with HIV negative pregnant women. Due to oxidative stress, when highly induce it is involved in tissue damage. These mechanisms lead to the decrease of the antioxidant capacity of the body in HIV positive pregnant women.
Authors and Affiliations
Rajesh Bhanudas Rajekar
Keywords
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