ANTIOXIDANT STUDIES ON METHANOL AND AQUEOUS EXTRACTS OF GYMNOSPORIA MONTANA PLANT
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2019, Vol 11, Issue 2
Abstract
Objective: The main objective of this study was to evaluate the free radical scavenging activity of methanol (70%) and aqueous extract of G. montana leaves which is a traditionally used herb known for its hepatoprotective activity. Methods: The in vitro antioxidant activity of G. montana extract was determined using 1, 1-diphenyl-2-picrylhydrazyl radical (DPPH), 2,2′-azinobis-(3-ethylbenzothiaziline-6-sulfonate (ABTS), Hydrogen peroxide scavenging activity, Superoxide anion radical scavenging activity and Reducing Power ability at three different concentrations (1.78µg/ml, 3.57µg/ml and 7.14µg/ml). Results: The Results revealed similar observations between the methanol and aqueous extract with respect to standard and showed potent antioxidant activity. Ascorbic acid was used as a standard, which showed IC50 value 4.71µg/ml, whereas, methanol and aqueous extract showed 5.08 µg/ml and 5.69 µg/ml. Three different concentrations were used which showed a dose-dependent non-significant increase in percent inhibition. Conclusion: Findings indicate that this plant is a good source of antioxidant and can be used for the treatment of diseases as such medicinal plant extracts are natural products and they are comparatively safe, eco-friendly, less expensive and locally available. Hence, the validation of the effects of these herbal remedies will have to be undertaken for their wider acceptance.
Authors and Affiliations
Nishat Ansari, Divya Chandel
Keywords
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- EP ID EP566038
- DOI 10.22159/ijpps.2019v11i2.30883
- Views 77
- Downloads 0
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