ANTITHYMOCYTE GLOBULIN, METHYLPREDNISOLONE AND CYCLOSPORINE IS AN EFFECTIVE TREATMENT IN SEVER APLASTIC ANEMIA.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2019, Vol 7, Issue 8
Abstract
Background: Immune suppressive therapy in severe aplastic anemia is considered now a standard treatment and it could be an alternative to the hemopoietic stem cell transplantation. Patients and methods: Thirteen Iraqi patients with severe aplastic anemia were included in this study. The place of work was in national center of hematology and center of bone marrow transplantation. They were treated with antithymocyte globulin infusion for 5 days, then continued on oral prednisolone for 28 days. The monitoring of the patients was done by complete blood count. Results: The response to the treatment was observed in 7 patients. 53% had CR and 38% had PR there was significant improvement in the WBC and platelet counts, but there were no significant changes in the HB levels. There was no difference between sex in response to treatment. Those patients who were considered non responders were six, the death rate was 15% and allergic reaction occur in one patient 7%. Conclusion: Antithymocyte globulin, methylprednisolone and cyclosporine is an effective treatment in severe aplastic anemia.
Authors and Affiliations
Basam Kamal Samad, Hussein Jasim Dadoosh Al-janabi, Qusay Sami Ahmed.
Keywords
Related Articles
- EP ID EP632443
- DOI 10.21474/IJAR01/9486
- Views 63
- Downloads 0
CHEMICAL LABORATORY SKILLS MEASUREMENT HIGH SCHOOL STUDENTS: DEVELOPMENT AND VALIDATION.
This study aims to develop the Student Labor Skills Worksheet and implementing to high school students in Ternate City. Development of Laboratory Skills Worksheet are adapted from four development stages (4-D): define, d...
ANALYSIS OF EARLY WARNING SYSTEM SCORE IMPLEMENTATION AT INPATIENT ROOM IN SILOAM HOSPITALS BALIKPAPAN.
This study aims to analyze the implementation of EWS according to standards and the factors that influence the implementation of EWS inpatient care Siloam Hospitals Balikpapan. The object in this study was Inpatient Room...
EVALUATION OF ANTIOXIDANT ACTIVITIES OF KOMBUCHA GREEN TEA.
Background and Aim:Kombucha Green Tea (KGT)a health promoting fermented beverage traditionally made by fermenting a sweetened green tea with a symbiotic culture of yeast species and acetic acid bacteria. This drink is co...
DETECTION AND MOLECULAR CHARACTERIZATION OF ESBL PRODUCING E. COLI ISOLATED FROM POULTRY DROPPINGS AND ITS ENVIRON.
Detection and molecular characterization of ESBL producing E. coli isolated from poultry droppings and its environ was investigated. Samples of poultry droppings (20), air (12), water (12) and soil (12) were collected fr...
EXAMINATION OF BIOACTIVITIES ACCORDING TO THE EXTRACTION CONDITIONS OF CIRSIUM JAPONICUM VAR. USSURIENSE.
This study was carried out to obtain a basic data for application in meat products via examination of bioactive materials from Cirsium japonicum var. Ussuriense tuber. Hot water extract showed high activities against BC...