Antitumor applications of nano-traditional Chinese medicine
Journal Title: Traditional Medicine Research - Year 2019, Vol 4, Issue 5
Abstract
An article by Deng et al. [1] that was first published in ACS Nano in 2019 revealed that nanoparticles extracted from cuttlefish ink (CINPs) could inhibit tumor growth by synergizing immunotherapy and photothermal therapy. The researchers found that these CINPs, which had significant antitumor efficacy, could effectively reprogram tumor-associated macrophages (TAMs) from the immune-suppressive M2-like phenotype to the antitumor M1-like phenotype. There were reportedly approximately 18.1 million new cancer cases and 9.6 million cancer-related deaths in 2018 worldwide [2]. As of 2015, the mortality rate from malignant tumors accounted for 23.91% of all causes of death in China, and this rate is still on the rise [3]. The pathogenesis of human tumors is the result of multiple factors jointly influencing gene expression, which implies that these tumors have low controllability. Hence, it is a topic of wide concern in clinical settings.
Authors and Affiliations
Jing-Na Zhou, Guo-Wei Zhang
Keywords
Related Articles
- EP ID EP49632
- DOI 10.12032/TMR20190813129
- Views 226
- Downloads 0
The potential effects of Caper (Capparis spinosa L.) in the treatment of diabetic neuropathy
Diabetic neuropathy (DN) is the most common form of neuropathy worldwide, with its prevalence rising alongside diabetes, and being characterized by sensory, motor or autonomic symptoms. DN is considered to be an incurabl...
A multi-center randomized controlled clinical trial of three-step acupuncture and cupping therapy for cervicogenic headache
Objective: To assess the clinical efficacy and safety of three-step acupuncture and cupping therapy for cervicogenic headache (CEH). Methods: A randomized, single-blind, multi-center, parallel controlled clinical trial w...
Acupuncture and/or moxibustion for the treatment of lumbar disc herniation: quality assessment of systematic reviews
Objective: In the current systematic review on acupuncture and/or moxibustion for lumbar disc herniation (LDH), we evaluated the methodology and quality of evidence and reports to provide necessary information for accura...
The regulation of method of tonifying Qi and activating blood circulation in the related gene expressions after spinal cord injury
The regulation of the genes including AQP4 gene, Bcl-2 gene, NF gene, Caspase gene, IL gene, NF-κB gene, TNF gene and HSP to treatment Spinal Cord Injury (SCI) by method of tonifying Qi and activating blood circulation w...
Evaluating the clinical efficacy of Thunder-Fire moxibustion combined with ovulation monitoring in the treatment of adenomyosis combined with infertility
This study evaluated the clinical efficacy of Thunder-Fire moxibustion combined with ovulation monitoring for the treatment of adenomyosis-associated infertility. A series of 120 patients diagnosed with uterine adenomyos...