Antitumor applications of nano-traditional Chinese medicine
Journal Title: Traditional Medicine Research - Year 2019, Vol 4, Issue 5
Abstract
An article by Deng et al. [1] that was first published in ACS Nano in 2019 revealed that nanoparticles extracted from cuttlefish ink (CINPs) could inhibit tumor growth by synergizing immunotherapy and photothermal therapy. The researchers found that these CINPs, which had significant antitumor efficacy, could effectively reprogram tumor-associated macrophages (TAMs) from the immune-suppressive M2-like phenotype to the antitumor M1-like phenotype. There were reportedly approximately 18.1 million new cancer cases and 9.6 million cancer-related deaths in 2018 worldwide [2]. As of 2015, the mortality rate from malignant tumors accounted for 23.91% of all causes of death in China, and this rate is still on the rise [3]. The pathogenesis of human tumors is the result of multiple factors jointly influencing gene expression, which implies that these tumors have low controllability. Hence, it is a topic of wide concern in clinical settings.
Authors and Affiliations
Jing-Na Zhou, Guo-Wei Zhang
Keywords
Related Articles
- EP ID EP49632
- DOI 10.12032/TMR20190813129
- Views 252
- Downloads 0
The marriage of Chinese Imperial Medicine and China Academy of Chinese Medical Sciences: privilege and benefits for the people
On September 27, 2019, the Palace Museum and China Academy of Chinese Medical Sciences held a signing ceremony of strategic cooperation at Jingsheng Zhai (The studio of esteemed excellence) in the garden of Jianfu Gong (...
Analysis of the action mechanism of Fang Ji Huang Qi decoction in treating rheumatoid arthritis by network pharmacology
Objective: To explore the pharmacological action mechanism of Fang Ji Huang Qi decoction (FHD) in the treatment of rheumatoid arthritis (RA) by network pharmacology. Methods: The chemical compositions and functional targ...
Clinical evidence and potential mechanisms of Chinese medicines for the treatment of diabetic retinopathy
Diabetic retinopathy is one of the main causes of visual impairment and blindness on a global scale. At present, the limitations of anti-vascular endothelial growth factor agents, steroids, laser photocoagulation, and vi...
Molecular docking study on the molecular mechanism of rhaponticin for treatment of chronic myelocytic leukemia
Molecular docking can not only design drugs for the targets, but also detect mechanism of drug effecting on the targets. This study researched the interaction of rhaponticin and genes associated with chronic myelocytic l...
Acupuncture and/or moxibustion for the treatment of lumbar disc herniation: quality assessment of systematic reviews
Objective: In the current systematic review on acupuncture and/or moxibustion for lumbar disc herniation (LDH), we evaluated the methodology and quality of evidence and reports to provide necessary information for accura...