Antral Follicle Count in Normal (Fertility-Proven) and Infertile Indian Women
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 1
Abstract
Antral follicle count (AFC) has been labeled as the most accurate biomarker to assess female fecundity. Unfortunately, no baseline Indian data exists, and we continue using surrogate values from the Western literature (inferred from studies on women, grossly different than Indian women in morphology and genetic makeup). Aims: To establish the role of AFC as a function of ovarian reserve in fertility-proven and in subfertile Indian women. To establish baseline cut-off AFC values for Indian women. Materials and Methods: Thirty patients undergoing workup for infertility were included and compared to equal number of controls (women with proven fertility). The basal ovarian volume and AFC were measured by endovaginal. USG the relevant clinical data and hormonal assays were charted for every patient. Statistical Analysis Used: SPSS platform was used to perform the Student’s t-test and Mann-Whitney U-test for intergroup comparisons. Correlations were determined by Pearson’s ranked correlation coefficient. Results: Regression analysis revealed the highest correlation of AFC and age in fertile and infertile patients with difference in mean AFC of both the groups. Comparison of the data recorded for cases and controls showed no significant difference in the mean ovarian volume. Conclusions: AFC has the closest association with chronological age in normal and infertile Indian women. The same is lower in infertile women than in matched controls. Baseline and cut-off values in Indian women are lower than that mentioned in the Western literature.
Authors and Affiliations
Dr Sanjay Kumar Chowdhury
Keywords
Related Articles
- EP ID EP273380
- DOI -
- Views 70
- Downloads 0
Use of Immunohistochemistry in Prostatic Carcinoma
Introduction: Use of immunohistochemistry in prostatic carcinoma Materials and Method: All specimens of Prostatic needle biopsy received during the period of 9 months from 2012 October to 2013 June in the Department of P...
Observation of lipid profile in individuals suffering from diabetes mellitus of different age groups, sex and socioeconomic status in Bihar
Introduction: Diabetes mellitus is a clinical syndrome characterized by hyperglycemia due to absolute or relative deficiency of insulin hormone. Type 2 Diabetes mellitus (DM) is characterized by insulin resistance, impai...
Wilms' Tumor in Children: An Experience of SIOP Protocol from Tertiary Centre
Background: Wilms’ tumor is the commonest renal .tumor. Survival depends on stage and biologic behavior and economic settings. International Society of Pediatric Oncology (SIOP) has laid down protocol for developing coun...
Thoracic Wall Defect with Ectopia Cordis: A Case Report
Introduction: Ectopia cordis is a rare congenital condition that is defined by the abnormal position of the heart outside the thorax associated with defects in the parietal pericardium, diaphragm, sternum, and, in most c...
Acute Kidney Injury (AKI) After Cardiac Surgery: Incidence, Risk Factors and Outcome
Background: Acute kidney injury (AKI) occurs in up to 30% of patients who undergo cardiac surgery and is associated with substantial morbidity and mortality. There is very limited data regarding the post cardiac surgery...