Aortic stent infection in etiology of fever of unknown origin in a geriatric patient
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2012, Vol 2, Issue 0
Abstract
Objective: Aortic stent greft infections (ASGI) are associated with significant morbidity and mortality. ASGI may exist as a seldom cause of fever. Case report: A 67 year-old male patient presented with fever, fatigue, chest pain and night sweats for a week. He had no infection sign except 3/6 systolic murmur. He admitted to the clinic with a prediagnosis of infective endocarditis. Combination therapy with ceftriaxon (2 g/day) + vancomycine (2 g/day) was administered. No vegetation was seen on neither transthoracic nor transesophageal ecocardiography. Methicillinsensitive Staphylococcus aureus (MSSA) yielded in blood cultures. Antibiotherapy was changed to sulbactam-ampicilline (8 g/day). Then, we learned that the patient has an aortic stent placed due to aortic dissection. Contrast enhancement was detected in magnetic resonance imaging. Cardiovascular surgeons decided not to remove the stent because of increased mortality; therefore antimicrobial therapy was extended to 4 weeks. But soon after discharge from the hospital, the patient re-admitted with fever. Sulbactam-ampicilline was begun, and MSSA yielded in blood cultures again. Antibiotherapy was continued for an additional 6 weeks. No recurrent infection occurred during 6 months of follow-up. Conclusion: ASGI could be one of the causes of fever of unknown origin (FUO). Despite the recommended treatment of ASGI being surgery, longterm conservative antimicrobial treatment may be performed successfully in patients with high surgical risk.
Phenolic extracts of Centaurium erythraea with novel antiradical, antibacterial and antileishmanial activities
Objective: To evaluate the antiradical, antibacterial and antileishmanial properties of phenolic extracts of Centaurium erythraea (methanol: MECE, ethanol: EECE, n-hexane: HECE, ethyl acetate: EACE) from north-west of Mo...
Prevalence of Necator americanus infection and risk factors among school-age children in Mirab Abaya District, South Ethiopia
Objective: To determine prevalence of hookworms, species identification, risk factors and its contribution to anemia in school-age children. Methods: In 2013, a cross-sectional study of intestinal parasitic infections wa...
Phytochemical analysis and standardization of Strychnos nux-vomica extract through HPTLC techniques
Objective: The objective is to develop a noval qualitative and quantitative method by which we can determine different phytoconstituents of Strychnos nux-vomica L. Methods: To profile the phyconstituents of Strychnos nux...
Up regulation of K A I 1 gene expression and apoptosis effect of imatinib mesylate in gastric adenocarcinoma (AGS) cell line
Objective: To evaluate the effect of imatinib mesylate on KAI1 gene expression and apoptosis properties in human gastric carcinoma AGS cell line. Methods: Cell viability was assessed by MTT assay and quantitative real ti...
Anthelmintic potential of Helicteres isora bark extract against Pheretima posthuma
Objective: To evaluate anthelmintic potential of Helicteres isora (H. isora) bark extract in Indian adult earthworms. Methods: The H. isora bark and Indian adult earthworms (Pheretima posthuma) were collected and authent...