AOVERVIEW AND MANAGEMENT OF POLYCYSTIC OVARIAN SYNDROME WITH TREATMENT MODULATION
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2017, Vol 3, Issue 4
Abstract
Many women with poly cystic ovarian syndrome are obese. Our study investigated that overweight people deals with endocrinopathy are women with in the reproductive age affecting about 6-8 % of age group. This disorder in morbidity women with PCOS –a major risk factor for the development of heart diseases, strokes and type II diabetes. Materials and methods: The study is a prospective observational study with retro-selective data collection among 72 people of gynecology department in a government hospital Tenali. Study setting: The study was conducted in the gynecology department in a government hospital Tenali AP India. Study duration: The duration of the study was from [April-September] 6 months. Study design: The current study was design as a cross section and uni centric study. Exclusion criteria: Long term treatment and age above 34 and BMI above 34, lactating, pregnancy, older-age, children and breast cancer patients are excluded from the study. Results: Out of 72 women’s managed with PCOS with a period of 6 month study with age of 22-34- and BMI of above 30. Who had underground weight loss surgery between Jan-April of these 61 patients were included for analysis.majority of female were students n=54 followed by public servants n=18. All the women n=72 [100%] ultrasonography of abdomen suggestive of PCOS, menstrual disturbance. The women had fertility desired ovulated on clomiphene citrate, metformin and also NORMOZ (chromium, picolinate, d-chiroinositol, myoinositol, vit-D3) and the pregnancy rate was increased with respectively. Discussion: PCOS is a complex endocrine disorder associated with an aggravated by obesity, weight loss, has been demonstrated to decrease insulin and androgen levels as well as to improve the clinical manifestations of PCOS. The raised levels of androgens, estrogens, insulin and LH explain the classic PCOS presentation on hirsutism, an ovulation or dysfunctional bleeding and also glucose metabolism dysfunction. Conclusions: Our study concluded that patients with PCOS who undergone Clomiphene citrate induction and Normoz (chromium, picolinate, D- chiroinositol, myo –inositol vit-D3), are of great benefit. Therefore need for further studies PCOS in development countries so as to bring the various treatment modalities on improvement of ovulation rates, menstrual cycles and pregnancy rates. Under the guidance of clinical pharmacist resistance and regularity on medication will increase the chance of getting pregnancy.
Authors and Affiliations
Dr. Kanamala Arun Chand Roby
Keywords
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