Aplastic Anemia in a Developing Country: The Present and the Need
Journal Title: National Journal of Laboratory Medicine - Year 2016, Vol 5, Issue 3
Abstract
Introduction: Aplastic anemia (AA) a rare, yet a life threatening hematological disorder. Aplastic anemia if untreated results in very high mortality. Early diagnosis of Aplastic anemias is essential for appropriate management of the patient. Aim: The aim of the study was to know the incidence of the disorder at our institution and categorize the patients into AA of varying severity aiding in their management protocol. Materials and Methods: Study was conducted retrospectively between January 2011 to June 2012, and prospectively from july 2012 to December 2013 in the Department of Pathology at our institution. The peripheral blood, bone marrow aspiration and biopsy were slides assessed for various hematological parameters. Results: Aplastic anemia has a male preponderance and bi modal age distribution. Anemia and thrombocytopenia were the commonest clinical manifestations. Conclusion: A good knowledge on clinical and hematological parameters will certainly aid in early diagnosis of Aplastic anemia and sub-categorization for treatment. But in a developing country financial constraints and lack of awareness forms a major drawback in providing an apt patient management. Thus, management of aplastic anemia in a developing country is definitely a challenging task. It is the need of the hour that tertiary centers such as ours create awareness amongst the general population and develop hospital policies for a holistic approach in the management of aplastic anemia.
Authors and Affiliations
Dr. Ashwini BR, Dr. Seetu Palo, Dr. Siddiq M Ahmed
Time and Motion Study of Blood Delivery System in a Regional Blood Transfusion Centre in West Bengal: A Pilot Study
Introduction: Delay in turnaround time (TAT) of blood delivery for transfusion is an important administrative problem in hospitals. Time and motion study for a definite root cause analysis (RCA) is valuable to identify t...
Seroprevalence of Hepatitis B Virus in Pregnant Women at a Tertiary Care Hospital of Eastern India
Introduction: Hepatitis B virus is a DNA virus causing hepatitis in humans. It is thought to be responsible for chronic liver diseases in 75% of cases. Besides other routes, vertical transmission from mother to child is...
A Study on the Biological Reference Interval of Vitamin D in North-East India
ABSTRACT Introduction: Vitamin D is the generic name given to all steroids that exhibit the biological activity of Cholecalciferol and derived from 7-dehydrocholesterol. Vitamin D has a major role in maintenance of healt...
Spectrum of Pediatric Malignancies at a Tertiary Care Centre in Western Uttar Pradesh
Introduction: Pediatric malignancies, although uncommon, are amongst the leading causes of death in children. These tumors show a distinctive incidence, histology and biological behaviour from those in adults. Aim: This...
Granular Ameloblastoma of Jaw: A Rare Histopathological Entity
Ameloblastoma is a benign odontogenic tumor of epithelial origin. Granular ameloblastoma is a rare subtype of ameloblastoma. In most of the cases, it is found admixed with other patterns of ameloblastoma. Pathogenesis of...