Apo A1/Msp1 polymorphismsin relation to Apo A-I and HDL-cholesterol levelin coronary artery disease patients with andwithout type II diabetes mellitus
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 5, Issue 3
Abstract
A common Mspl polymorphism (G/A) in the promoter region of the APOAl gene (-75 bp) has been shown to be associated with plasma apo A-I and HDL-C variation in several, but not all, studies. Recently another Msp I polymorphic site (± ) in the 5’ region of APOAl ( + 83 bp) has been identified which may also be relevant to HDL metabolism. This study was undertaken to elucidate the individual and combined effects of these two polymorphisms on plasma apo A-I and HDL-C levels in a case control study of 109 coronary artery disease patients.
Authors and Affiliations
Sachu Philip, Philips Abraham
Keywords
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