APPLICATION OF CHITOSAN IN THE FORMULATION OF HYDROGELS APPLIED ON SKIN
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2013, Vol 0, Issue
Abstract
These studies concerned the effect of composition on the substrate physicochemical parameters of hydrogels for use on skin. Hydrogels containing 1% of hydrocortisone and 1% of chitosan addition was made on the basis of methylcellulose, sodium carboxymethylcellulose and Carbopol 934 P. The release proceeds according to first-order kinetics. Depending on the type and composition of the polymer gels were obtained with various pharmaceutical availability of hydrocortisone. Addition of 1% chitosan affects the acceleration of the release in any given case
Authors and Affiliations
Jan Meler, Maria Szcześniak, Bożena Grimling, Janusz Pluta
INFLUENCE OF DIFFERENT CHANGES ON BIOAVAILABILITY OF MEDICINE CHITOSANS ANTIPHLOGISTIC DRUGS
The increased adsorption of anti-inflammatory drugs on polymer with pH increased from 7.6 to 8.0 may be explained by the swelling properties of chitosan, which increase with increasing environmental pH to alkaline levels...
INFLUENCE OF UV-IRRADIATION ON MOLECULAR WEIGHT OF CHITOSAN
In the present paper the results regarding the influence of UV-irradiation with 254 nm wavelength on the molecular weight of chitosan are presented. The concentration of chitosan solution was 0.5%(w/w) in 0.1 M acetic ac...
CELL BINDING AND PENETRATION OF QUATERNIZED CHITOSAN DERIVATIVES
Chitosan (Ch) is an attractive biopolymer with multiple reactive groups. However it is poorly soluble at neutral pH. Quaternization improves its solubility and permits the development of various positively charged drug d...
Studies on the Dyeing of Chitin and Chitosan with pre-metallised Dyes at Neutral pH
Both 1:1 pre-metallised acid dyes and pre-coppered direct dyes, but not 1:2 pre-metallised acid dyes, have been shown to readily dye chitin and chitosan from neutral dyebaths. With the 1:1 pre-metallised acid dyes the ad...
INFLUENCE OF A CALCIUM ALGINATE ON THE PROPERTIES OF HYDROPHILIC GELS CONTAINING LACTIC ACID COMPLEX WITH CHITOSAN
Treatment of vagina inflammatory condition is usually long and difficult because of its frequent relapse. The investigated preparations on methylcellulose base revealed good adhesion to the vaginal mucosa and were presen...