Application of Dental Implants Coated with Titanium Nitride: The Experimental Study with Porphyromonas gingivalis Infection
Journal Title: International Journal of Current Microbiology and Applied Sciences (IJCMAS) - Year 2017, Vol 6, Issue 1
Abstract
Dental implants have been effective for oral rehabilitation. Surface modification of implants is reportedly very important in achieving excellent osseointegration. In this study, a titanium nitride (TiN)-coated implant was evaluated using experimental infections in animals for use in dental implants. TiN-coated implants not only have optimal surface roughness to achieve osseointegration, but also have antimicrobial activity against Porphyromonas gingivalis, which is a pathogen in peri-implantitis. The present study demonstrated that TiN-coated implants showed less P. gingivalis surface adhesion and less bone resorption induced by P. gingivalis. In addition, the bone implant contact ratio of TiN-coated implants showed the highest percentage, with significant differences compared to machined, sandblasted, acid-etched, and radiofrequency magnetron sputter hydroxyapatite-coated surface modifications, even with P. gingivalis infection. This was the first report to demonstrate that TiN-coated implants were excellent for inducing osseointegration and inhibiting P. gingivalis infection using a simplified animal model.
Authors and Affiliations
Koutaro Yamazaki, Izumi Mashima, Futoshi Nakazawa, Yasuhiro Nakanishi, Morio Ochi
Keywords
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- EP ID EP567271
- DOI 10.20546/ijcmas.2017.601.017
- Views 49
- Downloads 0
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