Application of Design of Experiments (DOE) to the Development and Validation of a Swab Sampling Method for Cleaning Validation
Journal Title: Asian Journal of Chemistry and Pharmaceutical Sciences - Year 2017, Vol 2, Issue 1
Abstract
Cleaning validation is one of the key elements of the validation program of an active pharmaceutical ingredient (API)manufacturer. One of the most important aspects of cleaning validation is the sampling methods. Swabbing or surface sampling is the subject of this article. The application of sequential experimental designs for the efficient development of a swab sampling method, based on a fractional factorial design followed by full factorial design, is illustrated in this article
Authors and Affiliations
Keywords
Related Articles
- EP ID EP462821
- DOI 10.18311/ajcps/2017/8460
- Views 96
- Downloads 0
Editorial
no abstract
Whey Protein and Nigella sativa Oil Mitigate Potassium Dichromate Induced Hepatic Injury, Oxidative Stress and Hematotoxicity in Rats
The present study was carried out to evaluate the antioxidant property of whey protein and/orNigella sativaOil (NSO)against hepatotoxicity evoked by potassium dichromate(K2Cr2O7). Designed for this purpose, we detected t...
Biological Potential and Chemical Properties of Pyridine and Piperidine Fused Pyridazine Compounds: Pyridopyridazine a Versatile Nucleus
Pyridopyridazine compounds are important nitrogen atom containing heterocyclic compounds due to their pharmacologicalversatility. This heterocycle system characterized a structural feature for different types of bioactiv...
Synthesis, Characterization and Anti-Bacterial Activity of Isatin Schiff Base Derivatives
The lipid content and fatty acid profile of four marine macro algae (Ulva lactuca, Sargussum wightii, Sargussum turbinaria, andKappaphycus alvarezii) that are collected from south east coast of Sri Lanka were studied by...
Some Conventional and Convenient Process for Functionalization of 6-Phenyl-4,5-Dihydropyridazinone Compounds
The pyridazinone derivatives, particularly those bearing substituted different group or atom at a different position, haveattracted considerable attention due to their characteristic pharmacological and other anticipated...