Application of diffusion kurtosis imaging technology in evaluating early mild traumatic brain injury
Journal Title: TMR Integrative Medicine - Year 2020, Vol 4, Issue 11
Abstract
Objective To explore the value of magnetic resonance diffusion kurtosis imaging in diagnosing early tiny changes of brain tissue after mild traumatic brain injury. Methods A total of 22 patients with mild traumatic brain injury (study group) and 20 healthy subjects (control group) were enrolled in this study, and diffusion kurtosis imaging magnetic resonance scanning was employed in all subjects. fractional anisotropy, fractional anisotropy of kurtosis, mean kurtosis, axial kurtosis and radial kurtosis of diffusion kurtosis imaging parameters in the genu of corpus callosum, splenium corporis callosi, internal capsule, thalamus, putamen, cortex of frontal lobe, temporal lobe and parietal lobe at control group, the injured side and the mirror regions were measured, and the results were compared between the two groups. The receiver operating characteristic curve was used to evaluate the ability of different parameters in diagnosing mild traumatic brain injury. Results Compared with the control group, in the study group fractional anisotropy values of bilateral genu of corpus callosum, splenium corporis callosi, internal capsule and thalamus were significantly reduced, and fractional anisotropy of kurtosis values of bilateral thalamus and putamen were significantly reduced, and the differences were statistically significant (P＜0.05). Compared with the control group, in the study group mean kurtosis and axial kurtosis values of bilateral genu of corpus callosum, posterior limb of Internal capsule, thalamus, putamen and cortex of temporal lobe were significantly reduced, while radial kurtosis values in the genu of corpus callosum, thalamus, cortex of frontal lobe, temporal lobe at the injured side were increased, and the differences were statistically significant (P ＜ 0.05). Conclusion DKI techniques can sensitively detect the early tiny pathologic changes of cerebral tissue in mild traumatic brain injury patients, which provide more imaging evidence for the clinical early diagnosis treatment and prognosis.
Authors and Affiliations
Zhi-jie Zhang, Wei Liu, Guo-shi LV, Zheng Pan, Xiao-min Liu, Bo Wang
Keywords
Related Articles
- EP ID EP683439
- DOI 10.12032/TMRIM202004011
- Views 259
- Downloads 0
Analysis of 54 cases of COVID-19
Objective: The clinical features and test results of 2019-nCoV pneumonia (COVID-19) were analyzed retrospectively in order to understand the diagnostic significance of clinical test index, and to summarize the experienc...
Traditional Chinese medicine in antiviral treatment
The Novel Coronavirus (COVID-19), which broke out in Wuhan, China in December 2019, attracted worldwide attention. With a long incubation period and strong infectiousness, COVID-19 poses a great threat to the life and he...
Target prediction of Chrysanthemum morifolium against hepatocellular carcinoma
A novel computational system was used to decipher the targets and mechanisms of Chrysanthemum morifolium against hepatocellular carcinoma. The putative target profile of Chrysanthemum morifolium against hepatocellular ca...
Cinnamomum camphora: a long history for epidemics control
Camphor (C10H16O) is a white crystalline solid exist in enantiomeric form R and S camphor. It is a terpenoid obtained from turpentine oil. Synthetically it is synthesized by catalytic process as alpha pinene. Naturally c...
Effects of mindfulness-based stress reduction therapy on anxiety and depression in patients with maintenance hemodialysis: a meta analysis
Objective: This study aimed to evaluate the effects of mindfulness-based stress reduction therapy on anxiety and depression in patients with maintenance hemodialysis. Methods: CNKI, VIP, WanFang, CBM, Embase, the Cochran...