Application of metal complexes of schiff base with special reference to thiosemicarbazone: a review
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2014, Vol 2, Issue 1
Abstract
Schiff bases have been shown to exhibit a broad range of biological activities, including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. Thiosemicarbazone derivatives are used in organic synthesis and they are used in evaluating new product that possesses different biological activities. This review covers updated information on the most active Thiosemicarbazone derivatives that have been reported to show considerable pharmacological actions such as, anticonvulsant, antidepressant and other biological activity. The Chemistry of Schiff bases is a field that is being no- ticed. Schiff base ligands are considered privileged li- gands because they are easily prepared by a simple one pot condensation of an aldehyde and primary amines. In this review, the synthesis, biological activities along with application of Schiff base and their complexes are summarized from 1976-2013.
Authors and Affiliations
Devesh Kumar*| Agra College, Dr B.R. Ambedkar University, Agra (U.P.), India., Dr Vipin Kumar Singh| Agra College, Dr B.R. Ambedkar University, Agra (U.P.), India.
Keywords
Related Articles
- EP ID EP1464
- DOI -
- Views 480
- Downloads 21
Unilateral Spinal Anaesthesia For Toilet Mastectomy-As An Alternative To General Anaesthesia: A Case Report
General anaesthesia is a choice of anaesthesia for surgeries of breast like modified radical mastectomy (MRM). But patients with lung disease like bronchial asthma, COPD, poor pulmonary function are at a high risk for pe...
A Clinical study of Virechana Karma and Jaloukavacharana (Leech Therapy) in Ekakushtha w.s.r. to Psoriasis
Psoriasis is a disease which affects the skin and joints. It commonly causes red scaly patches to appear on the skin. Psoriasis is a papulosquamous disorder of the skin, characterized by sharply defined erythematousquamo...
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF SOME 1,3,4-OXADIAZOLE DERIVATIVES WITH BENZOXAZOLE MOIETY
Synthesis of 1,3,4-oxadiazole derivatives has attracted considerable attention in view of therapeutic applications. In the presented research work, a series of novel 5-substituted-1,3,4-oxadiazole-2-thiol containing pipe...
Possible Study of Drug-Drug Interactions between Lisinopril and Gliclazide in Experimental Animals
The most often problem in type II diabetic patients coexists with hypertension, the incidence of hypertension among diabetic patients is high. In this case, use a combination of medicine unavoidable (Polypharmacy). In su...
PRESENT STATUS OF PHARMACY EDUCATION AND FUTURE PROSPECTS AND CHALLENGE OF PHARMACY PRACTICE IN BANGLADESH
Pharmacy is a multi-disciplinary subject composed of all aspects of drugs including its manufacturing, synthesis, quality control and quality assurance, marketing, handling, safety matters, patients care, invention, and...