Application of optical coherence tomography in maculopathy of high myopia
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 5
Abstract
AIM: To investigate the value of optical coherence tomography(OCT)in maculopathy of high myopia. <p>METHODS: Totally 50 patients(50 affected eyes)with high myopia who were admitted to our hospital during the period from June 2016 to May 2017 were prospectively enrolled in the observation group, and 50 normal healthy people(50 eyes)were selected as the control group at the same time. All subjects completed the conventional ophthalmic examination and OCT after admission. The visual acuity, intraocular pressure, diopter, eye axis, macular thickness and morphological changes were recorded, and detection of maculopathy of high myopia by different examination methods was statistically analyzed. <p>RESULTS: Conventional ophthalmic examination showed that the macular region was normal in 37 eyes and abnormal in 13 eyes(26%)while OCT showed that it was normal in 12 eyes and abnormal in 38 eyes(76%)in the observation group. The rate of maculopathy detected by OCT was higher than that by conventional ophthalmologic examination, with a significant difference(<i>P</i><0.05). The rates of subretinal or choroidal neovascularization and macular epiretinal membrane detected by OCT were higher than those by conventional ophthalmologic examination, with significant differences(<i>P</i><0.05). There was no significant difference in the proportion of normal results between conventional ophthalmologic examination and OCT in the control group(<i>P</i>>0.05). The intraocular pressure, diopter and axial length of patients with high myopia and maculopathy were higher/longer than those of the control group, the BVCA was worse than that of the control group, the thickness of retinal macular region, thickness of nerves above and below the optic disc, thickness of optic nerves on the bitamporal and nasal sides of the optic disc were lower than those of the control group, with significant differences(<i>P</i><0.05). <p>CONCLUSION: OCT can quantitatively determine the thickness of nerve fiber layer around the retina in patients with high myopia, and clearly display the characteristics of maculopathy, which can provide reliable quantitative data for the diagnosis of maculopathy of high myopia.
Authors and Affiliations
Fang-Lei Lou
Comparison on biomechanical stability between femtosecond laser assisted LASIK and LASEK with ocular response analyzer
AIM: To compare the difference of biomechanical stability after a femtosecond laser-assisted <i>in situ</i> keratomileusis(FS-LASIK)and laser-assisted subepithelial keratomileusis(LASEK)by ocular response analyzer(ORA)....
Expressions of Bcl-2, Bax and Ki67 in the primary pterygium
AIM: To research the expressions of B-cell lymphoma gene 2(Bcl-2), Bcl-2 associated X-protein(Bax)and Ki67(proliferating cell marker)in the primary pterygium and normal bulbar conjunctiva, to explore the pathogenesis of...
Diagnosis and management of familial exudative vitreoretinopathy
Familial exudative vitreoretinopathy(FEVR)is a rare inherited disorder of retinal angiogenesis. It is characterized by avascular peripheral retina. Mutations in FZD4, NDP, LRP5, TSPAN12, ZNF408, KIF11 have been found the...
Intravitreal Ranibizumab injection combined with trabeculectomy and PRP for neovascular glaucoma
AIM: To determine the medium term efficacy of intravitreal ranibizumab injection combined with subsequent trabeculectomy and panretinal photocoagulation(PRP)for the treatment of neovascular glaucoma(NVG). <p>METHODS: In...
Orthoptic parameters and asthenopic symptoms analysis after 3D viewing at varying distances
AIM: To analyse visual modifications such as amplitude of accommodation, near point of convergence(NPC)reopsis and near phoria associated with asthenopic symptoms after 3D viewing at varying distances.<p>METHODS: A prosp...