AQP2 Genes and Nephrogenic Diabetes Insipidus: A Review
Journal Title: Annual Research & Review in Biology - Year 2015, Vol 8, Issue 6
Abstract
Nephrogenic Diabetes insipidus (NDI) is an issue coming about because of lacking against diuretic hormone (ADH) activity and is described by the entry of extensive measures of exceptionally dilute urine. This problem must be separated from other polyuric states, for example, essential polydipsia, osmotic diuresis and diabetes mellitus. Diabetes insipidus is a condition when a person is passing urine with excess of water, this condition arise due to improper re-absorption of water during urine formation. Aquaporins (AQPs) play a important role in absorption of water. AQP2 is quite dominant than other isoforms. This article provides nutshell information about Diabetes Insipidus and role of Aquaporin-2 gene in its physiology.
Authors and Affiliations
Monica Soni, Arvind Pareek
Keywords
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- EP ID EP353595
- DOI 10.9734/ARRB/2015/22224
- Views 86
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