Are Mean Platelet Volume and Neutrophil-to- Lymphocyte Ratio Valuable in The Early Detection of System Involvements in Henoch-Schönlein Purpura?
Journal Title: HASEKİ TIP BÜLTENİ - Year 2018, Vol 56, Issue 4
Abstract
Aim: Henoch-Schönlein purpura (HSP) is the most common type of vasculitis in childhood, and severe complications due to intestinal and renal involvement can be observed. In this study, it was planned to investigate the value of mean platelet volume (MPV) and neutrophil-tolymphocyte ratio (NLR) in early detection of system involvement in HSP. Methods: A total of 119 patients diagnosed with HSP and 75 healthy controls were included in the study. Data on age, gender and physical examination as well as complete blood count, complete urine examination and faecal occult blood test were obtained from the files of the patients. Results: Gastrointestinal system (GIS) involvement was detected in 41 patients (34.45%), renal involvement in 35 patients (29.41%) and arthritis was detected in 21 patients (17.65%). It was determined that the mean hemoglobin (p=0.02) and MPV values (p=0.0001) o were significantly lower and the mean leukocyte (p=0.0001), platelet (p=0.0001), neutrophil (p=0.0001) count and NLR value (p=0.0001) were significantly higher in patients than in controls. No statistically significant difference was observed in the MPV and NLR values between patients with and without GIS involvement, renal involvement and arthritis. Conclusion: It is thought that MPV and NLR cannot be used as laboratory parameters in the early detection of system involvement in HSP.
Authors and Affiliations
Abdulrahman Özel, Özlem Bostan Gayret, Meltem Erol, Özgül Yiğit, Fatih Mete
Keywords
Related Articles
- EP ID EP436369
- DOI 10.4274/haseki.4164
- Views 81
- Downloads 0
The Use of Negative Pressure Therapy for the Treatment of the Defects on Extremities due to High-Energy Trauma
Aim: Defects of the extremities due to high-energy trauma are common and it is necessary to repair these defects. Reconstruction is possible with simple surgeries using skin grafts and negative pressure therapy (NPT). In...
Comparison of Forced-air Warming Systems and Intravenous Fluid Warmers in the Prevention of Pediatric Perioperative Hypothermia
Aim: We aimed to compare the efficacy of intravenous blood-fluid warming and forced-air warming systems for the prevention of perioperative hypothermia in pediatric patients under six years of age. Methods: Two-hundred c...
Traumatic Middle Cerebral Artery Occlusion: A Case Report
Traumatic occlusion of the middle cerebral artery (MCA) is a rare cause of cerebral infarction. Malignant infarction of the MCA is associated with a mortality rate of 80%. Arterial dissection, cerebral vasospasm, and thr...
Diagnostic Value of Elastosonographic Evaluation of Cervix in Idiopathic Recurrent Spontaneous Miscarriage in the First Trimester
Aim: To detect prognostic role of cervical elastosonography (ES) among women with a history of idiopathic recurrent spontaneous miscarriage (IRSM) in early pregnancy. Methods: There were 40 women enrolled in the study. O...
Analysis of Childhood Mortality in Emergency Department
Aim: The aim of the present study was to analyze the mortality rate, demographic characteristics and cause of death in pediatric patients who were referred to our emergency department. Methods: Patients aged 0-18 years w...