Are quinolone eardrops safe? New data on the association with persistent tympanic membrane perforation
Journal Title: Archives of Otolaryngology and Rhinology - Year 2017, Vol 3, Issue 3
Abstract
Recently Alrwisan et colleagues [1] compares the rates of tympanic membrane (TM) perforation after use of the two available classes of eardrops, quinolones and neomycin, following ear tube surgery. Considering a total of 96,595 children, they found an increased risk of TM perforation requiring tympanoplasty in children which used quinolone eardrops. The adjusted hazard ratios were 1.49 (95% confidence interval [CI], 1.05–2.09) for ofloxacin, 1.94 (95% CI, 1.32–2.85) for ciprofloxacin plus hydrocortisone, and 2.00 (95% CI, 1.18–3.41) for ciprofloxacin.
Authors and Affiliations
Lovato Andrea
Keywords
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- EP ID EP352157
- DOI 10.17352/2455-1759.000051
- Views 45
- Downloads 0
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