Are quinolone eardrops safe? New data on the association with persistent tympanic membrane perforation
Journal Title: Archives of Otolaryngology and Rhinology - Year 2017, Vol 3, Issue 3
Abstract
Recently Alrwisan et colleagues [1] compares the rates of tympanic membrane (TM) perforation after use of the two available classes of eardrops, quinolones and neomycin, following ear tube surgery. Considering a total of 96,595 children, they found an increased risk of TM perforation requiring tympanoplasty in children which used quinolone eardrops. The adjusted hazard ratios were 1.49 (95% confidence interval [CI], 1.05–2.09) for ofloxacin, 1.94 (95% CI, 1.32–2.85) for ciprofloxacin plus hydrocortisone, and 2.00 (95% CI, 1.18–3.41) for ciprofloxacin.
Authors and Affiliations
Lovato Andrea
Keywords
Related Articles
- EP ID EP352157
- DOI 10.17352/2455-1759.000051
- Views 50
- Downloads 0
A Questionnaire Survey: Knowledge in Upper Airway Infections among General Practitioners in Malaysia
Background: Upper respiratory tract infections (URTI) cases are one of the most frequently seen cases in the primary care setting. The causative agents are either bacteria or virus. It is not easy to differentiate among...
Positional Changes in the Hyoid Bone, Hypopharynx, Cervical Vertebrae, and Cranium Before and After Correction of Glosso-Larynx (CGL)
Introduction: Respiratory inhibition by ankyloglossia with deviation of the epiglottis and larynx (ADEL) was thought to be caused by tongue muscles. But to explain this effect by the tongue muscles alone was unreasonable...
Aggressive Thyroid Gland Carcinoma: A Case Series
In 2017 there were approximately 62000 new cases of thyroid cancer (TC) in the United States, with a death toll of less than 5%. This relatively low mortality rate is based on a grouping of all TC subtypes, which masks t...
The Risks of Hemostaic Material in Tonsillectomy
Importance: Surgicel is an effective hemostat either for intra or post-operative bleedings, but should be used cautiously in the case of tonsillectomy. Some surgeons choose to leave pieces of surgicel in the tonsils bed...
Management of Intra-operative Chyle Leak during Neck Dissection: Recognition and Control
Chyle fistula (CF) is a rare complication of neck dissection. The extravasation of chyle can result in potentially devastating metabolic, nutritional and immunologic sequellae. We report the efficacy a protocol for trea...