Arsenic Exposure and the Risk of Cancer
Journal Title: Advances in Clinical Toxicology - Year 2021, Vol 6, Issue 2
Abstract
It is known that exposure to environmental chemicals increases the risk of cancerous and non-cancerous pathologies. Geomedical and anthropic evidence indicates that there is a close relationship between increased morbidities from cardiovascular diseases and cancer among the population in the Antofagasta Region and the etiology of exposure to arsenic. The most commonly used drugs with chemotherapy are platinum-based. The present work characterizes short-term urinary evacuation, that is, the pooled urine excreted 24 hours after the first cycle of treatments of cancer patients with cisplatin or carboplatin. The inorganic biochemical status and behavior of excreted As, Se and Pt administered to and evacuated by patients could be involved in the post-treatment quality of life of the patients and the evolution and final outcome of the disease. There were 90 patients in the group, 32 with lung cancer and 58 with different cancers termed “other types of cancerâ€, as well as 10 patients untreated with platinum-based drugs. Platinum and selenium were determined by ICP-OES and As by HGAAS. The detection limits were 7.7, 5.4 and 0.2 (ng/mL), respectively.
Authors and Affiliations
Pizarro I* and Roman D
Keywords
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