Arsenic- Exposure, Mechanism of Action and Toxicity Analysis: A Prenatal View
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 7
Abstract
Arsenic continues to poison the drinking water of thousands across the globe. Numerous studies have evaluated the carcinogenic potential of lifetime exposure and also the ill effects of prenatal exposure. Population Studies have revealed the strong correlation between the development of skin, bladder, kidney and lung cancer and arsenic exposure in endemic areas. Although the adult exposure outcomes continue to be evaluated, the prenatal exposure aspect is neglected in most studies. Our study aims to explore the co carcinogenic effect of prenatal arsenic exposure. Most experiments conducted so far in this topic utilizes models of adult exposure and very few studies have reported association of prenatal exposure to any type of carcinogenesis. This study will address the underlying mechanisms behind this association. The knowledge derived from the study can be used to develop or design early life detection markers for in utero arsenic exposure and the anomalies that may ensue.
Authors and Affiliations
Shagun Shukla
Keywords
Related Articles
- EP ID EP526945
- DOI -
- Views 66
- Downloads 0
Evaluation of Awareness of Common Eye Diseases among General Population of Bihar
Objectives: The main objective of this study is to assess the awareness level of common eye related problems in population of Bihar. Material & Methods: a cross-sectional type of study was conducted on 422 general popula...
Congenital Hypertrophic Pyloric Stenosis At A Tertiary Care Hospital: A Surgical Experience With 30 Infants
Background: Congenital hypertrophic pyloric stenosis (CHPS), first described in 1888 by Harald Hirschsprung, is one of the most common cause of gastric outlet obstruction in infants. The incidence is approximately 1–4 pe...
A Study on Haemodialysis Vsperitoneal Dialysis in Acute & Chronic Renal Failure
Background: Over the past few decades, Dialysis has become more effective in the management of acute & chronic renal failure and poisonings (Acute kidney injury). There are a number of studies which recommend either peri...
Burden of HCV infection among pregnant women with assessment of risk factors and pregnancy outcome in HCV infected: A hospital based study from Uttarakhand
Introduction: Hepatitis-C is a global health problem. Risk factors for HCV infection include intravenous drug use, transfusion of infected blood or blood products, unsafe therapeutic injections and surgical, dental proce...
Anti Mullerian Hormone Levels and Antral Follicle Count as Predictors of In Vitro Fertilisation Outcomes
Objective: To study the role of Anti Mullerian hormone levels and antral follicle count in predicting the outcomes in IVF cycles. Methods: A prospective study was done in fifty women with infertility undergoing IVF treat...