Assesment of Prothrombin Time, APTT and Fibrin Degradation Product as Predictor of DIC & HELLP Syndrome in Case of Pregnancy Induced Hypertension
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 3
Abstract
Abstract: Pregnancy induced hypertension (PIH) is divided into three clinical types: pre-eclampsia, eclampsia, and gestational hypertension. It has been recorded that the maternal utero-placental blood flow decreases in pre-eclampsi because of maternal vasospasm. Reduced maternal utero placental blood flow leading indirectly to constriction of fetal stem arteries has been associated with the changes seen in the placentas of women with pre-eclampsia. Maternal vasospasm leads to fetal hypoxia. The agent responsible for vasospasm has still not been isolated precisely, but it seems certain to be humoral in origin. To assess the Prothrombin time, APTT and Fibrin degradation product among cases with Pregnancy Induced hypertension (study group) as predictor of DIC & HELLP syndrome. To perform Prothrombin time, APTT and Fibrin degradation product in patient of PIH and control. To assess the profile as predictor of DIC and HELLP syndrome among them. There was high sensitivity, specificity of PT, APTT and FDP in predicting DIC, HELLP and in differentiating DIC from HELLP.
Authors and Affiliations
Dr. Sanjeev Narang, Dr. Vikas Misra, Dr. Anjali Singh, Dr. Parul Dargar, Dr. Priyanka Pandey
Keywords
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