Assessing the Anticancer Effect of the <i>Euphorbia condylocarpa</i> Plant on AGS Gastric Cancer Cell Line
Journal Title: Gene, Cell and Tissue - Year 2017, Vol 4, Issue 1
Abstract
Background Spurge family is a large family of plants that contains more than 300 genera and 800 species of which 5 genera and 72 species are native to Iran. This important family of plants can be used in various disease treatments such as cancer, arthritis, asthma, bacterial infections, and neuralgia. This study investigated the anticancer effects of the alcoholic extract of <i>Euphorbia condylocarpa</i> whose native Iranian Kurdish name is “Shoalehkolah”. Methods In this study, the cytotoxicity of the methyl extracts of <i>Euphorbia</i> was performed on AGS gastric cancer cell lines using the MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide) assay. The cytotoxicity of the methyl extract of <i>Euphorbia condylocarpa</i> with dilutions of 10, 20, 100, and 200 μg/mL was considered. Results The obtained data showed that the greatest effect was related to the dilution of 200 μg/mL. Conclusions The findings suggest that the methyl extract of this plant can be considered for its anticancer effects.
Authors and Affiliations
Sepideh Mohammadi, Arash Mahboubi, Masumeh Mohammadi, Mehdi Hedayati, Arsalan Jalili
Keywords
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- EP ID EP235766
- DOI 10.17795/gct-41223
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