Assessment and Comparison of Liver Functions in Leprosy
Journal Title: International Journal of Current Research and Review - Year 2017, Vol 9, Issue 5
Abstract
Leprosy is chronic infectious disease of man, caused by Mycobacterium leprae, affecting peripheral nerves, skin and sometimes other tissues. Hepatic involvement is seen in all stages of the leprosy, more so in lepra reactions. Aim: The present study was undertaken to evaluate hepatic status by studying the various liver function tests in leprosy patients as well as in patients of lepra reaction. Methodology: Sixty untreated leprosy patients (30 Multibacillary, 30 Paucibacillary) with duration of illness varying from one month to three years were considered. Hepatic functional status was evaluated by estimation and comparison of variations in the levels of liver enzymes, proteins (Albumin, Globulin) and Australia antigen in paucibacillary, multibacillary leprosy and type I&2 lepra reactions. Results: Deceased levels of serum albumin were noted in all forms of leprosy except in type II reaction while serum globulins were decreased only in paucibacillary leprosy. Raised levels of SGOT were found in all forms of leprosy including lepra reactions. However SGPT was significantly raised in type II lepra reaction. Serum bilirubin was raised in type II lepra reaction while raised levels of serum alkaline phosphatase were observed in type I lepra reaction. Serum cholesterol levels were decreased in all forms of leprosy except in type I reactions. Conclusion: We found that liver is significantly affected in leprosy and in lepra reactions. Assessment of liver functions is useful to measure the severity of affection of the liver in leprosy and for monitoring the patients on antileprosy treatment..
Authors and Affiliations
Dr. Archana G. Dhavalsahankh
Keywords
Related Articles
- EP ID EP602486
- DOI -
- Views 121
- Downloads 0
Rare Case of Capillary Hemangioma of Bilateral Lower Limb: A Case Report
Aim: The aim of this case report is to bring to light an unusual case of soft tissue tumor in a young female. Case Report: Hemangiomas are commonly occuring soft tissue tumors, but it rarely involves the feet. We are rep...
Spectrum of Clinical Presentation of Intracranial Tuberculoma
Objectives: To describe the clinical presentation, radiological findings in 15 patients with intracranial tuberculoma. Design: Consecutive cases admitted with tuberculoma to the MBGH Hospital, Udaipur, Rajasthan, were in...
Profile of Metal Accumulation in Aquatic Macrophytes
Industrial development coupled with population growth has resulted in the over exploitation of natural resources. Life support systems viz; water, air and soil are thus getting exposed to an array of pollutants especiall...
Formulation of Cost Effective Alternative Bacterial Culture Media Using Fruit and Vegetables Waste
Vegetable stalks and fruit peels are generally used for composting or merely disposed off as waste. Considering their nutritional values, these kitchen wastes can be utilized for production of alternative cultivation med...
Statistical Modelling for Job Satisfaction of Maharashtra State Road Transport Corporation Key Members
Mobility is one of the characteristics of human beings; movement is the feature of human nature which simply means mere movement of persons from one place to another for getting comfort journey. Bus conductors and Driver...