Assessment of Alteration in Coagulation Parameters in Patients with PCOS: An Observational Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Background: Polycystic Ovarian Syndrome (PCOS) is one of the most common endocrine system disorders that affect women in their reproductive age. Alterations in the coagulation profile of the patients have been reported in the past literature in patients with PCOS. Hence; under the light of above mentioned data, we planned the present study to assess the alterations occurring in coagulation parameters in patients with PCOS. Materials & Methods: The present study included evaluation of alterations in the coagulation profile of the patients with PCOS. A total of 85 patients diagnosed with PCOS were included in the present study. A total of 85 age-matched healthy controls were included in the present study. All the patients were called in the morning and fresh blood samples were collected. Samples were sent to pathology department for assessment of haematological and coagulation parameters. All the results were compiled on Microsoft excel sheet and were evaluated by SPSS software. Results: Mean fibrinogen and D-Dimer levels of the subjects of the PCOS group were 3.40 g/l and 0.22 mg/l respectively. Mean fibrinogen and D-Dimer levels of the subjects of the control group was 2.80 g/l and 0.26 mg/l respectively. Factor VIII and vWF levels of the subjects of the PCOS group were 1.35 IU/mol and 0.99 IU/L respectively. Factor VIII and vWF levels of the subjects of the control group were 0.9 IU/mol and 0.87 IU/L respectively. Conclusion: Some amount of alteration in the coagulation profile does occur in PCOS patients.
Authors and Affiliations
Anuradha, Sunita Gulati
Keywords
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- EP ID EP540261
- DOI 10.21276/ijmrp.2018.4.2.082
- Views 70
- Downloads 0
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