ASSESSMENT OF ANALGESIC EFFICACY OF CLONIDINE AND FENTANYL WITH ROPIVACAINE IN THE SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK
Journal Title: International Journal of Medical and Biomedical Studies - Year 2018, Vol 2, Issue 6
Abstract
Ropivacaine, the S (-) enantiomer of N-(2,6- dimethylphenyl)-1-propyl-2-piperidinecarboxamide is a new long-acting local anesthetic like bupivacaine. Ropivacaine, compared to bupivacaine blocks pain transmitting A-delta and C fibers to a greater extent than A-beta fibers (controlling motor function). Ropivacaine has a wider margin of safety and is less cardiac & neurotoxic compared to bupivacaine with similar duration of action. The fentanyl and clonidine given with local anaesthetic in regional nerve block enhances the block by acting perineurally or it is because of systemic absorption of fentanyl and clonidine administered in block. The current study was planned to compare the efficacy of fentanyl and clonidine as an adjuvants and as an intravenous administration in supraclavicular plexus block with 0.75% ropivacaine. The study was planned in the Department of the Surgery undergoing the Anaesthesia in Sri Krishna Medical College and Hospital, Muzaffarpur, from Jan 2017 to Jun 2017. After obtaining proper informed consent, 40 adult patients of both sexes, aged 18 to 65 years, belonging to ASA I or II and undergoing supraclavicular brachial plexus block were enrolled for this study. The data from the [resent study concludes that the arliest onset of sensory and motor blockade as well as longer duration of analgesia resulted whe clonidine 150 µg was used as a perineural adjuvant to Ropivacane 0.75% with minimal side effects compared to its same dose given intravenously. Keywords: supraclavicular block, clonidine, fentanyl , ropivacaine, etc.
Authors and Affiliations
Dr. Krishna Kumar
Keywords
Related Articles
- EP ID EP485023
- DOI 10.32553/ijmbs.v2i6.105
- Views 42
- Downloads 0
FORMULATION AND EVALUATION OF ASPIRIN RELEASE FROM MATRIX PELLETS COMPRESSED INTO MUPS TABLET
The oral route of drug administration is the most important and most user-friendly route of administration. In recent years, Multiple Unit Pellet Systems (MUPS) tablets are widely used in solid dosage form design. MUPS i...
AQROECOLOGICAL SITUATION OF PROPOSALS, PROBLEMS AND SOLVING WAYS IN GARBAGE IN AZERBAIJAN
Afforestation and anthropogenic impacts of the primitive Torpag, grass cover and mainly pastures (degradation areas), degradation and degradation of forest ecosystems have led to considerable sharp reduction of the feed...
SPATIAL DATA INTERPOLATION
During the study and adjustment, techniques revealed our analysis of spatial data in vector format. The latter is best suited for the spatial analysis of discrete objects. However, when the spatial variable is represente...
CLINICAL PREVALENCE AND CAUSATIVE MICROBES RESPONSIBLE FOR NEONATAL SEPSIS IN NEONATES ADMITTED IN NMCH
Neonatal sepsis is of two types; early onset sepsis and late onset sepsis. Early onset sepsis (EOS) present within first 72 hours of life. In severe cases, the neonates may be symptomatic at birth. Infants with EOS usual...
COMPARATIVE ASSESSMENT OF DIFFERENT TYPES OF LARYNGOSCOPES BLADES - MACINTOSH, MILLER AND MCCOY FOR LARYNGEAL VIEW AND PRESSOR RESPONSE
The laryngoscopy is known to have profound cardiovascular effects. This includes pressor response and tachycardia along with an increase in catecholamine concentration, mainly norepinephrine. The major cause of the sympa...