Assessment of Biochemical Changes in Pregnancy Induced Hypertension (PIH) among Saudi Population at KAMC-Riyadh
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2016, Vol 15, Issue 10
Abstract
Background: One of the most common complications that affect around 2-5% pregnant women is elevated blood pressure defined as gestational hypertension. Aims & Objective: To compare and correlate between plasma urea, creatinine, sodium, potassium, and plasma glucose and urine protein in pre-eclamptic and normotensive groups. Materials and Methods: This is quantitative retrospective chart review study. It is an hospital based case control study involving data from 199 age – matched Saudi women, discharged from Obstetrics and Gynecology Department of King Abdul Aziz medical city during the period of 2013-2014. The data were collected following standard procedures and statistical analysis was done using independent t – test and correlation. Results: The levels urea, creatinine, sodium, potassium in the serum, plasma glucose and urine protein were significantly elevated in pre-eclamptic women when compared to normotensives (p= 0.000, p= 0.000, p= 0.005, p= 0.000, p= 0.000, p= 0.000 respectively). There was a significant positive correlation between urea and protein, urea and creatinine (r=0.3 P=0.002), (r=0.7 p=0.000) respectively. Conclusion: The elevated values of serum creatinine, urea, urine protein, sodium, potassium and plasma glucose preclude them to be useful for consideration as consistent predictive indicator(s) for pre-eclampsia or pregnancy related hypertension.
Authors and Affiliations
Tarig Karar, Mohamed Abdel Fattah, Khaled Romaizan O. Alenazy, Mohammad Jamaan Alharbi, Fares Meshabab S. Alqahtani, Waleed Al Tamimi, Ikram Al Hassan, Susan Grajo, Ivy Alquisalas, Shoeb Qureshi
Keywords
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- EP ID EP341498
- DOI 10.9734/BJMMR/2016/25024
- Views 86
- Downloads 0
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