Assessment of cardiovascular profile in metabolic syndrome patients: A clinical study

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Assessment of cardiovascular profile in metabolic syndrome patients: A clinical study

Journal Title: International Journal of Medical and Health Research - Year 2017, Vol 3, Issue 5

Abstract

Background: Metabolic syndrome is a clustering of at least three of the five following medical conditions such as abdominal (central) obesity, elevated blood pressure elevated fasting plasma glucose high serum triglycerides low high-density lipoprotein (HDL) levels. The present study was conducted to assess blood pressure and lipid profile in metabolic syndrome patients. Materials & Methods: This study was conducted in the OPD patients of department of general medicine in year 2014. It included 140 metabolic syndrome patients. All patients were subjected to fasting blood sugars and fasting lipid profile level measurements. Blood pressure was recorded in right upper limb with patient in sitting posture using standard sphygmomanometer and stethoscope with palpatory method. Blood samples for lipid profile were taken after 12 hours overnight fast. Results: Off 140 patients males were 70 and females were 70. In group I, 98 (70%) patients had hypertension while in group II none had hypertension. The difference was significant (P- 0.01). In group I, duration of hypertension in patients was <1years (6), 1-5 years (14), 5-10 years (26) and >10 years (52). Group II had no cases of hypertension. The difference was significant (P- 0.01). In group I patients, 18 had systolic B.P >160mm of Hg, 28 had in between 140-159mm of Hg, 72 had 120-139 mm of Hg and 22 had 90-119 mm of Hg. In group II, 2 had B.P >160mm of Hg, 4 had in between 140-159mm of Hg, 24 had 120-139 mm of Hg and 110 had 90-119 mm of Hg. The difference was significant (P- 0.01). In group II patients, 23 had diastolic B.P >100mm of Hg, 25 had in between 90-99mm of Hg, 80 had 80-89 mm of Hg and 12 had 60-79 mm of Hg. In group II, 5 had diastolic B.P >100mm of Hg, 7 had in between 90-99mm of Hg, 46 had 80-89 mm of Hg and 82 had 60-79 mm of Hg. The difference was significant (P- 0.01). Total cholesterol level between 150-200 mg/dl was seen in 65 in group I and 140 in group II subjects while >200 mg/dl was seen in 75 patients in group I only. Triglyceride level >150 mg/dl was seen in 105 patients in group I and 5 in group II while < 150mg/dl was seen in 35 in group I and 135 in group II subjects. LDL level in group I <150 mg/dl was seen in 80 in group I and 138 in group II while >150 mg/dl was seen in 60 in group I and 2 in group II subjects. VLDL level in group I <40mg/dl was seen in 30 in group I and 140 in group II while > 40 mg/dl was seen in 110 in group I patients. The difference in each category was significant (P < 0.01). HDL level in group I with >40 was seen in 60 patients 30-39 was seen in 50 patients and <29 was seen in 30 patients. In group II, >40 was seen in 120 patients 30-39 was seen in 15 patients and <29 was seen in 5 patients. The difference in each category was significant (P < 0.01). Conclusion: The change in life style, busy and hectic schedule, lack of physical exercise, intake of junk food, smoking and alcohol is among various contributory factors leading to metabolic syndrome. There is need to change the life style to prevent its occurrence.

Authors and Affiliations

Dr. Pulak Raj, Dr. Rajesh Kumar Khare

Keywords

metabolic syndrome smoking total cholesterol

EP ID EP585552
DOI -
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