Assessment of central and peripheral hemodynamics in children with sepsis by echocardiography and ultrasound dopplerography
Journal Title: Актуальна інфектологія - Year 2018, Vol 6, Issue 4
Abstract
Background. Sepsis is one of the most common causes of mortality in children. The severe course of sepsis is usually associated with the development of septic shock and multiple organ failure. An important component in the comprehensive examination and control of treatment effectiveness is the monitoring of hemodynamic parameters. Purpose: to evaluate changes in central and peripheral hemodynamics by echocardiography and Doppler ultrasound in children with sepsis. Materials and methods. A retrospective study of cases of septic shock in children aged 0 to 18 years who underwent treatment in the intensive care unit was conducted. Patients were monitored for central and peripheral hemodynamics by echocardiography and Doppler ultrasound. Results. One hundred eight cases of sepsis were investigated. Meningococcus was a causative agent in 53.7 % patients, in 0.9 % — Staphylococcus, in 0.9 % — Pneumococcus, in 0.9 % — Yersinia, and in 41.7 %, aetiology was not been established. In 12 children from the study group, fatal outcome occurred. Septic shock was associated with significantly higher heart rate and an increase in peripheral resistance indices in the abdominal trunk and renal arteries. Fatal course of the disease was associated with a high heart rate and a decrease in diastolic velocity (Vmin) in the abdominal trunk and renal arteries. Conclusions. Echocardiography and ultrasound dopplerography in children with sepsis make it possible to evaluate the pattern and extent of cardiovascular dysfunction. Results of regional blood flow assessment can be a diagnostic criterion for the septic shock and has prognostic value in children with sepsis.
Authors and Affiliations
V. V. Yevtushenko, V. O. Shadrin
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