Assessment of Colocasiaesculenta Mucilage as Suspending Agent in Paracetamol Suspension
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2017, Vol 3, Issue 7
Abstract
Abstract: The purpose of this study is to search for more affordable as well as effective natural excipients that can be used as viable alternative for the formulation of pharmaceutical suspension. The suspending properties of mucilage of Colocasiaesculenta were evaluated comparatively with those of compound tragacanth and acacia in Paracetamol suspension. Characterization tests were carried out on Colocasiaesculenta mucilage. Sedimentation volume, rheology, pH, degree of flocculation and redispersibility were the evaluation parameters. The values obtained were used as basis for comparison of the suspending agents studied. Colocasiaesculenta mucilage showed comparable suspending ability as acacia and compound tragacanth although Colocasiaesculenta mucilage was found to be less viscous than acacia and compound tragacanth. Also, the redispersibility of the materials was found to be in the order: Colocasiaesculenta mucilage > Acacia > Compound Tragacanth. The Study indicates that Colocasiaesculenta mucilage may be useful as a pharmaceutical adjuvant and as a suspending agent. Keywords: Paracetamol, suspension, suspending agent, mucilage, Colocasiaesculenta.
Authors and Affiliations
Alalor CA, Augustine K
Keywords
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