Assessment of Diagnostic Efficacy of CT Scan and MRI in Detecting Brain Tumors
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Background: Tumors in the intracranial region can arise from brain, skull, embryonic tissues, spinal cord, pituitary gland and meninges. A complete and thorough evaluation of the patient needs to be performed for the appropriate diagnosis. The steps include complete history, physical examinations with special emphasis on neurologic examination, and diagnostic neuroimaging studies like CT scan and MRI. The aim of the present study is to establish the sensitivity and specificity of CT scan and MRI in diagnosing brain lesions compared to results obtained by biopsy. Materials and Methods: The present retrospective experimental study was conducted at few Private Radiodiagnostic Centers. The study included all the patients who reported with brain tumor to the OPD of the department. Complete detail about the patient was obtained from the hospital’s record. It included patient’s demographics, medical history. Patient’s confidentiality was maintained throughout the study. The results obtained from CT scan and MRI was compared with those obtained from biopsy. SPSS software was used for analysis. Results: The present study included 300 subjects who reported to the department with brain tumor. The mean age of the subjects was 32.78 +/- 21.6 years. The sensitivity of CT scan in this study was 82.7% and specificity was 33.3%. The positive predictive value is 94% and negative predictive value was 14%. On applying fischer test, there is no significant difference in the results obtained by biopsy and CT scan. The sensitivity of MRI is 92% and specificity is 33%. The positive predictive value is 94% and negative predictive value is 28%. On applying fischer test, there was no significant difference in the results obtained by MRI and biopsy as the p value was more than 0.05. Conclusion: From the study we can conclude that both CT scan and MRI are useful assets as diagnostic aids. MRI being more sensitive than CT scan. In cases were biopsy specimens are scarce or biopsy specimens cannot be obtained, they can be diagnosed by imaging modalities.
Authors and Affiliations
Karnawat Shekhar, Vishwas Chakra v
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