Assessment of Efficacy of Drug and Nondrug Treatments in Hypertensive Patients: A Comparative Study
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 4
Abstract
Background: A number of studies have reported that use of antihypertensive drugs in hypertensive patients gradually decreases the morbidity and mortality rates. But, it is quite inappropriate to prescribe anti-hypertensive drugs to one-fifth of young population with mild hypertension for long durations. Several clinical trials investigated the efficacy of non-pharmacological interventions and lifestyle modifications to reduce BP. The present study was planned to assess the efficacy of pharmacological and non-pharmacological management of hypertension. Materials and Methods: The present study was conducted in the Department of General Medicine, KPC Medical College and Hospital, Jadavpur, Kolkata, West Bengal (India). For the study, selection of 100 patients with mild hypertension was done. Clinical criteria were used for the selection of all patients. Participants were randomly grouped into 2 groups, Group 1 and Group 2. Patients in group 1 were prescribed 50 mg of atenelol drug once a day. On the contrary, no drug was prescribed in Group 2 rather subjects in this group were advised physical exercise such as brisk waking for 50-60 minutes. The blood pressure values were measured before starting the study, at 2 weeks, 4 weeks, 6 weeks and at 8 weeks using sphygmomanometer. Results: The mean age of the patients that participated in the study was 45.23+12.42 years with age range being 21-60 years. The number of male patients was 68 whereas female patients were 32 in number. The mean age of patients in group 1 was 44.89 + 12.43 years and in group 2 was 47.64 + 8.9 years. In group 1, the number of male patients was 38 and female patients were 12. Similarly, in group 2, the number of male patients was 30 and female patients were 20. At 8 weeks there was significant reduction in the blood pressure as compared to baseline values. Conclusion: From the results of current study, we conclude that pharmacological and non-pharmacological methods, both are effective in lowering blood pressure in hypertensive patient. The pharmacological method is statistically significant as compared to non-pharmacological method.
Authors and Affiliations
Ujjal Kr. Chakravarty, Santanu Bhakta
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